SCHEMBL29437945

SCHEMBL29437945

Nc1ccccc1-c1nc2ccccc2s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 1.00
NPC1 O15118 8/20 1.00
RAB9A P51151 8/20 1.00
MEN1 O00255 6/20 1.00
KMT2A Q03164 6/20 1.00
ALDH1A1 P00352 6/20 1.00
MAPT P10636 5/20 1.00
SMN1; SMN2 Q16637 4/20 1.00
GAA P10253 3/20 1.00
TDP1 Q9NUW8 2/20 1.00
L3MBTL1 Q9Y468 2/20 1.00
ILK Q13418 5/20 0.59
APP P05067 4/20 0.59
MMP9 P14780 1/20 0.59
MMP8 P22894 1/20 0.59
POLB P06746 2/20 0.58
HSD17B10 Q99714 2/20 0.58
THRB P10828 1/20 0.58
ALOX15 P16050 1/20 0.58
CASP1 P29466 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL914476 1.00 KDM4E (1.00) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL28252291 0.93 RAB9A (0.87) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL19350362 0.91 RAB9A (0.82) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL31451587 0.89 KDM4E (0.79) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL27854305 0.87 KDM4E (0.75) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL231307 0.86 KDM4E (0.75) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL4602546 0.85 RAB9A (0.73) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL12854008 0.84 KDM4E (0.72) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL25327971 0.84 MAPT (0.71) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL29478092 0.84 MAPT (0.71) KDM4ENPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115417866-B Benzothiazole derivative for detecting hydrazine, preparation method and application thereof, and kit for detecting hydrazine 湖南超亟检测技术有限责任公司 2025-04-08 CN claimed
CN-118146174-A D-A organic fluorescent small molecule based on 2- (2-aminophenyl) benzothiazole, preparation method and application thereof in phosgene and sarin detection 吉林大学 2024-06-07 CN claimed
CN-115353498-B Benzothiazole zinc ion fluorescent probe and preparation method thereof 坛墨质检科技股份有限公司 2023-08-08 CN claimed
CN-113912596-B Benzothiazole matrix-based palladium ion detection fluorescent probe and preparation method and application thereof 江苏科技大学 2022-12-02 CN claimed
CN-115417866-A Benzothiazole derivative for detecting hydrazine, preparation method and application thereof, and hydrazine detection kit 湖南超亟检测技术有限责任公司 2022-12-02 CN claimed
CN-115353498-A Benzothiazole zinc ion fluorescent probe and preparation method thereof 坛墨质检科技股份有限公司 2022-11-18 CN claimed
CN-109971465-B Multifunctional fluorescent probe with ESIPT (electron fluorescence tomography) and AIE (electron emission tomography) properties and preparation method and application thereof 渤海大学 2022-03-18 CN claimed
CN-119912403-B D-A type organic fluorescent small molecule, preparation method and application thereof in detection of nitrofurans antibiotics 吉林大学 2025-12-05 CN disclosed
CN-119912403-A D-A type organic fluorescent small molecule, preparation method and application thereof in detection of nitrofurans antibiotics 吉林大学 2025-05-02 CN disclosed
CN-119912403-A D-A type organic fluorescent small molecule, preparation method and application thereof in detection of nitrofurans antibiotics 吉林大学 2025-05-02 CN disclosed
CN-115417866-B Benzothiazole derivative for detecting hydrazine, preparation method and application thereof, and kit for detecting hydrazine 湖南超亟检测技术有限责任公司 2025-04-08 CN disclosed
CN-115417866-B Benzothiazole derivative for detecting hydrazine, preparation method and application thereof, and kit for detecting hydrazine 湖南超亟检测技术有限责任公司 2025-04-08 CN disclosed
CN-118146174-A D-A organic fluorescent small molecule based on 2- (2-aminophenyl) benzothiazole, preparation method and application thereof in phosgene and sarin detection 吉林大学 2024-06-07 CN disclosed
CN-113912596-B Benzothiazole matrix-based palladium ion detection fluorescent probe and preparation method and application thereof 江苏科技大学 2022-12-02 CN disclosed
CN-115353498-A Benzothiazole zinc ion fluorescent probe and preparation method thereof 坛墨质检科技股份有限公司 2022-11-18 CN disclosed
CN-111995599-B Ratio-type fluorescent molecular probe and preparation method and application thereof 中南大学 2022-07-01 CN disclosed
CN-114591264-A Fluorescent probe for indicating pH value and preparation method and application thereof 湖南超亟检测技术有限责任公司 2022-06-07 CN disclosed
CN-112239431-B Method for preparing 2-benzothiazole substituted aniline compound by catalysis of copper compound 广州大学 2022-05-13 CN disclosed
CN-109971465-B Multifunctional fluorescent probe with ESIPT (electron fluorescence tomography) and AIE (electron emission tomography) properties and preparation method and application thereof 渤海大学 2022-03-18 CN disclosed
CN-109971465-B Multifunctional fluorescent probe with ESIPT (electron fluorescence tomography) and AIE (electron emission tomography) properties and preparation method and application thereof 渤海大学 2022-03-18 CN disclosed