Rosmarinic Acid

Rosmarinic Acid

SCHEMBL29438187

O=C(/C=C/c1ccc(O)c(O)c1)O[C@H](Cc1ccc(O)c(O)c1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 4/20 1.00
▸ MMP1 P03956 4/20 1.00
▸ KDM4E B2RXH2 3/20 1.00
▸ MAPT P10636 3/20 1.00
▸ HSD17B10 Q99714 3/20 1.00
▸ SRC P12931 3/20 1.00
▸ POLB P06746 2/20 1.00
▸ GAA P10253 2/20 1.00
▸ HPGD P15428 2/20 1.00
▸ RECQL P46063 2/20 1.00
▸ APP P05067 2/20 1.00
▸ LCK P06239 2/20 1.00
▸ AKR1B1 P15121 2/20 1.00
▸ CYP1A2 P05177 1/20 1.00
▸ KDM1A O60341 1/20 1.00
▸ USP2 O75604 1/20 1.00
▸ TTR P02766 1/20 1.00
▸ JUN P05412 1/20 1.00
▸ FYN P06241 1/20 1.00
▸ THRB P10828 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rosmarinic Acid SCHEMBL29482753 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL29482752 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL29371115 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL7458453 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL1650675 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL19348 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL15263386 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL29453379 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL15263387 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL30521740 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115006326-A Purslane soothing mask and preparation method thereof 杭州孔凤春化妆品股份有限公司 2022-09-06 — — CN claimed
CN-111876447-B Strain and method for producing rosmarinic acid 陕西鸿道生物分析科学技术研究院有限公司 2022-04-01 — — CN claimed
CN-120788974-B Double-drug-peptide drug-loading system and preparation method and application thereof 南京中医药大学 2026-05-19 — — CN disclosed
CN-117143852-B Histone deacetylase SmHDA6 and application of encoding gene thereof in regulation and control of salvianolic acid accumulation 浙江中医药大学 2026-05-19 — — CN disclosed
EP-4593978-A1 METHOD FOR DEPLETING PYRROLIZIDINE ALKALOIDS IN COMFREY ROOT EXTRACTS BY MEANS OF LIQUID-LIQUID CHROMATOGRAPHY RotaChrom Technológiai Zrt. (HU) 2025-08-06 — — EP disclosed
CN-118320178-B Preparation and application of injectable hydrogel for repairing infectious bone defect 三峡大学 2025-04-22 — — CN disclosed
CN-119307468-B Salvia Miltiorrhiza rosmarinic acid synthetase mutant with improved enzyme activity, preparation method and application 浙江中医药大学金华研究院 2025-04-22 — — CN disclosed
US-12274769-B2 Skincare compositions THE BOOTS COMPANY PLC (GB) 2025-04-15 — — US disclosed
CN-119700785-A Rosmarinic acid and scutellarin compatible composition and application thereof 中国医学科学院药物研究所 2025-03-28 — — CN disclosed
US-12252716-B2 Strain and method for producing rosmarinic acid Hong-Taoism Research Institute of analytical science and technology LTD., Shaanxi Province (CN) 2025-03-18 — — US disclosed
CN-112512559-B Compositions and methods for treating NRP 2-related diseases ATYR 医药公司 2025-02-28 — — CN disclosed
US-20220273529-A1 SKINCARE COMPOSITIONS THE BOOTS COMPANY PLC (GB) 2022-09-01 — — US disclosed
US-20220244263-A1 METHODS FOR TREATING SMALL CELL NEUROENDOCRINE AND RELATED CANCERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-04 — — US disclosed
WO-2022155545-A1 LOOP-MEDIATED ISOTHERMAL AMPLIFICATION (LAMP) ANALYSIS FOR PATHOGENIC TARGETS PURDUE RESEARCH FOUNDATION (US) 2022-07-21 — — WO disclosed
CN-114747689-A Biological agent for improving meat quality and preparation method and application thereof 南京农业大学 2022-07-15 — — CN disclosed
EP-3341371-B1 ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS UNIV PALACKEHO (CZ) 2022-06-29 — — EP disclosed
CN-110292544-B Preparation method of rosemary hydrolat rich in rosmarinic acid 湖南先伟阳光生物科技有限公司 2022-06-10 — — CN disclosed
US-20220105017-A1 TOPICAL MACQUI BERRY FORMULATION TRACIE MARTYN INT INC (US) 2022-04-07 — — US disclosed
CN-111876447-B Strain and method for producing rosmarinic acid 陕西鸿道生物分析科学技术研究院有限公司 2022-04-01 — — CN disclosed
CN-114191426-A Compound extract of radix bupleuri, angelica sinensis and mint as well as preparation method and application thereof 成都中医药大学 2022-03-18 — — CN disclosed
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