Rosmarinic Acid

Rosmarinic Acid

SCHEMBL1650675

O=C(/C=C/c1ccc(O)c(O)c1)O[C@H](Cc1ccc(O)c(O)c1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 4/20 1.00
▸ MMP1 P03956 4/20 1.00
▸ KDM4E B2RXH2 3/20 1.00
▸ MAPT P10636 3/20 1.00
▸ HSD17B10 Q99714 3/20 1.00
▸ SRC P12931 3/20 1.00
▸ POLB P06746 2/20 1.00
▸ GAA P10253 2/20 1.00
▸ HPGD P15428 2/20 1.00
▸ RECQL P46063 2/20 1.00
▸ APP P05067 2/20 1.00
▸ LCK P06239 2/20 1.00
▸ AKR1B1 P15121 2/20 1.00
▸ CYP1A2 P05177 1/20 1.00
▸ KDM1A O60341 1/20 1.00
▸ USP2 O75604 1/20 1.00
▸ TTR P02766 1/20 1.00
▸ JUN P05412 1/20 1.00
▸ FYN P06241 1/20 1.00
▸ THRB P10828 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rosmarinic Acid SCHEMBL29482753 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL29482752 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL29438187 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL29371115 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL7458453 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL19348 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL15263386 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL29453379 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL15263387 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10
Rosmarinic Acid SCHEMBL30521740 1.00 TDP1 (1.00) TDP1MMP1KDM4EMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11400038-B2 Synergistic antioxidant compositions RODAN & FIELDS, LLC (US) 2022-08-02 — — US claimed
US-20210205198-A1 SYNERGISTIC ANTIOXIDANT COMPOSITIONS ANKURA TRUST COMPANY, LLC, IN ITS CAPACITY AS SUCCESSOR AGENT 2021-07-08 — — US claimed
US-10898423-B2 Synergistic antioxidant compositions RODAN & FIELDS, LLC (US) 2021-01-26 — — US claimed
US-20200261344-A1 SYNERGISTIC ANTIOXIDANT COMPOSITIONS ANKURA TRUST COMPANY, LLC, IN ITS CAPACITY AS SUCCESSOR AGENT 2020-08-20 — — US claimed
EP-3523020-A1 FLEXIBLE AND MULTI-FUNCTIONAL COACERVATES AND HYDROGEL MATERIALS Aarhus Universitet (DK) 2019-08-14 — — EP claimed
WO-2018065450-A1 FLEXIBLE AND MULTI-FUNCTIONAL COACERVATES AND HYDROGEL MATERIALS AARHUS UNIVERSITET (DK) 2018-04-12 — — WO claimed
EP-2817360-A1 MULTI-RESPONSIVE SELF-HEALING POLYMER AND GEL COMPOSITIONS Aarhus Universitet (DK) 2014-12-31 — — EP claimed
WO-2013123946-A1 MULTI-RESPONSIVE SELF-HEALING POLYMER AND GEL COMPOSITIONS AARHUS UNIVERSITET (DK) 2013-08-29 — — WO claimed
US-20110159017-A1 TRYTOPHAN CATABOLISM IN CANCER TREATMENT AND DIAGNOSIS LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) 2011-06-30 — — US claimed
EP-4672979-A1 COMPOSITIONS Givaudan SA (CH) 2026-01-07 — — EP disclosed
EP-4658091-A1 COMPOUNDS Givaudan SA (CH) 2025-12-10 — — EP disclosed
CN-121041165-A Preparation method of soft-light nourishing hair oil 广州市雅创化妆品有限公司 2025-12-02 — — CN disclosed
US-20250352593-A1 USE OF A MICROALGAE EXTRACT, ALONE OR IN COMBINATION, FOR IMPROVING COGNITIVE ABILITIES MICROPHYT (FR) 2025-11-20 — — US disclosed
CN-120193037-A Lactic acid bacteria extracellular polysaccharide grafted rosmarinic acid covalent compound and preparation method thereof 安徽农业大学 2025-06-24 — — CN disclosed
US-20090076143-A1 COMPOSITIONS AND METHODS FOR TREATING INFLAMMATION AND INFLAMMATION-RELATED DISORDERS BY PLECTRANTHUS AMBOINICUS EXTRACTS ACADEMIA SINICA (TW) 2009-03-19 — — US disclosed
US-20090076143-A1 COMPOSITIONS AND METHODS FOR TREATING INFLAMMATION AND INFLAMMATION-RELATED DISORDERS BY PLECTRANTHUS AMBOINICUS EXTRACTS ACADEMIA SINICA (TW) 2009-03-19 — — US disclosed
EP-1978930-A2 SUTURES AND ANTI-SCARRING AGENTS Angiotech Pharmaceuticals, Inc. (CA) 2008-10-15 — — EP disclosed
WO-2007089878-A2 SUTURES AND ANTI-SCARRING AGENTS ANGIOTECH PHARMACEUTICALS, INC. (CA) 2007-08-09 — — WO disclosed
WO-2006121522-A2 IMPLANTABLE SENSORS AND PUMPS, ANTI-SCARRING AGENTS, AND THERAPEUTIC COMPOSITIONS ANGIOTECH INTERNATIONAL AG (CH) 2006-11-16 — — WO disclosed
WO-2006121518-A2 ELECTRICAL DEVICES, ANTI-SCARRING AGENTS, AND THERAPEUTIC COMPOSITIONS ANGIOTECH INTERNATIONAL AG (CH) 2006-11-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090076143-A1 COMPOSITIONS AND METHODS FOR TREATING INFLAMMATION AND INFLAMMATION-RELATED DISORDERS BY PLECTRANTHUS AMBOINICUS EXTRACTS CCL11, IL1A, CXCL8 TDP1 4592/4885MMP1 496/4885KDM4E 3807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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