Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | AHR | P35869 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 5/20 | 0.56 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.55 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 2/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29438413 | 0.80 | HSD17B10 (0.73) | GAAAHRHSD17B10TMPRSS4HTT | |
| SCHEMBL23853488 | 0.78 | GAA (1.00) | GAAAHRHSD17B10KDRMEN1 | |
| SCHEMBL29438459 | 0.78 | GAA (1.00) | GAAAHRHSD17B10KDRMEN1 | |
| SCHEMBL29438425 | 0.78 | HSP90AA1 (0.57) | GAAAHRHSD17B10HTTKMT2A | |
| SCHEMBL5665935 | 0.78 | FADS1 (0.66) | GAATMPRSS4KDRGRM4PDK1 | |
| SCHEMBL29438436 | 0.77 | GAA (0.62) | GAAAHRHSD17B10MEN1HTT | |
| SCHEMBL6203625 | 0.77 | GAA (0.61) | GAAAHRHSD17B10TMPRSS4EPAS1 | |
| SCHEMBL31070247 | 0.76 | KDR (0.56) | TMPRSS4KDRGRM4RAF1PDGFRB | |
| SCHEMBL29438417 | 0.75 | CDK2 (0.65) | GAAAHRHSD17B10MEN1HTT | |
| SCHEMBL29438453 | 0.75 | GAA (0.59) | GAAAHRHSD17B10HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220064167-A1 | IMIDAZO-PYRAZOLE CARBOXAMIDE DERIVATIVES AS ANTICANCER AGENTS AND THE SYNTHESIS THEREOF | AVIDIN KFT. (HU) | 2022-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220064167-A1 | IMIDAZO-PYRAZOLE CARBOXAMIDE DERIVATIVES AS ANTICANCER AGENTS AND THE SYNTHESIS THEREOF | MYD88, MCL1, MYADM | GAA 4744/4885AHR 881/4885HSD17B10 4038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.