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Sugi Predict / Compounds / Bimosiamose

Bimosiamose

Bimosiamose

SCHEMBL29438584

O=C([O-])Cc1cccc(-c2cc(CCCCCCc3ccc(O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)c(-c4cccc(CC(=O)[O-])c4)c3)ccc2O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)c1.[Na+].[Na+]

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SELESELLSELP

The experimentally established mechanism targets of Bimosiamose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SELP known ✓ P16109 2/20 0.84
▸ SELPLG Q14242 1/20 0.84
▸ PPARG P37231 2/20 0.53
▸ PPARD Q03181 2/20 0.53
▸ PPARA Q07869 2/20 0.53
▸ SLC28A3 Q9HAS3 1/20 0.46
▸ ACHE P22303 1/20 0.44
▸ SLC5A1 P13866 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bimosiamose SCHEMBL14970212 0.92 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
Bimosiamose SCHEMBL26341832 0.92 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
Bimosiamose SCHEMBL29367817 0.92 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
SCHEMBL7620761 0.92 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
SCHEMBL7614341 0.92 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
Bimosiamose SCHEMBL2529148 0.92 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
Bimosiamose SCHEMBL12182030 0.92 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
Bimosiamose SCHEMBL29372538 0.92 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
Bimosiamose SCHEMBL14015902 0.92 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
Bimosiamose SCHEMBL2528669 0.91 SELP (0.98) SELPSELPLGPPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240123168-A1 PRODUCT DELIVERY DEVICES AND METHODS MUSTAPHA JIHAD A (US) 2024-04-18 — — US disclosed
EP-4255541-A1 PRODUCT DELIVERY DEVICES AND METHODS Breathe Restore, Inc. (US) 2023-10-11 — — EP disclosed
US-20230181847-A1 PRODUCT DELIVERY DEVICES AND METHODS BREATHE RESTORE INC (US) 2023-06-15 — — US disclosed
US-11672929-B2 Product delivery devices and methods BREATHE RESTORE, INC. (US) 2023-06-13 — — US disclosed
US-20220168516-A1 PRODUCT DELIVERY DEVICES AND METHODS BREATHE RESTORE, INC. 2022-06-02 — — US disclosed
EP-2704560-B1 ORGAN CARE SOLUTION FOR EX-VIVO MACHINE PERFUSION OF DONOR LUNGS TRANSMEDICS INC (US) 2022-04-06 — — EP disclosed