SCHEMBL2943909

SCHEMBL2943909

Cc1c(C(=O)O)ccc(C(C)C)c1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 2/20 0.50
GRM1 Q13255 1/20 0.47
CYP1A2 P05177 1/20 0.41
ALDH1A1 P00352 2/20 0.40
FABP3 P05413 1/20 0.39
FABP4 P15090 1/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TSHR P16473 1/20 0.38
NOTUM Q6P988 1/20 0.38
HAAO P46952 1/20 0.37
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2502805 0.86 GRM1 (0.46) ACE2GRM1CYP1A2ALDH1A1TSHR
SCHEMBL27588019 0.84 ACE2 (0.47) ACE2GRM1CYP1A2ALDH1A1FABP3
SCHEMBL5611626 0.84 ACE2 (0.47) ACE2GRM1CYP1A2ALDH1A1FABP3
SCHEMBL16789576 0.84 GRM1 (0.53) ACE2GRM1CYP1A2ALDH1A1FABP3
SCHEMBL20365188 0.83 ACE2 (0.39) ACE2GRM1TRPA1LMNACHRM1
SCHEMBL17112806 0.82 ACE2 (0.46) ACE2GRM1CYP1A2ALDH1A1FABP3
SCHEMBL7220806 0.82 ACE2 (0.46) ACE2GRM1CYP1A2ALDH1A1FABP3
SCHEMBL30409815 0.82 ACE2 (0.46) ACE2GRM1CYP1A2ALDH1A1FABP3
SCHEMBL31389208 0.82 CYP1A2 (0.58) GRM1CYP1A2ALDH1A1MEN1KMT2A
SCHEMBL128319 0.82 CYP1A2 (0.58) GRM1CYP1A2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1747059-A1 PERVAPORATION COMPOSITE MEMBRANES McMaster University (CA) 2007-01-31 EP claimed
US-20060000778-A1 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2006-01-05 US claimed
WO-2005102503-A1 PERVAPORATION COMPOSITE MEMBRANES MCMASTER UNIVERSITY (CA) 2005-11-03 WO claimed
EP-2226192-B1 DRYING SUBSTANCES, PREPARATION AND USE THEREOF ORIDION MEDICAL 1987 LTD (IL) 2016-08-31 EP disclosed
EP-2226116-B1 Drying tube, preparation and use thereof ORIDION MEDICAL 1987 LTD (IL) 2016-04-20 EP disclosed
CN-105001225-A Heterocyclic modulators of lipid synthesis 3 V BIOSCIENCES INC 2015-10-28 CN disclosed
US-20150283519-A1 DRYING SUBSTANCES, PREPARATION AND USE THEREOF ORIDION MEDICAL 1987 LTD. (IL) 2015-10-08 US disclosed
US-9090766-B2 Drying substances, preparation and use thereof ORIDION MEDICAL 1987 LTD. (IL) 2015-07-28 US disclosed
CN-103561576-B Heterocyclic modulators of lipid synthesis 3 V BIOSCIENCES INC 2015-07-22 CN disclosed
US-9067035-B2 Drying substances, preparation and use thereof ORIDION MEDICAL (1987) LTD. (IL) 2015-06-30 US disclosed
US-20140230652-A1 DRYING SUBSTANCES, PREPARATION AND USE THEREOF ORIDION MEDICAL (1987) LTD. (IL) 2014-08-21 US disclosed
EP-2226192-A1 Drying substances, preparation and use thereof Oridion Medical 1987 Ltd. (IL) 2010-09-08 EP disclosed
EP-2226116-A2 Drying substances, preparation and use thereof Oridion Medical 1987 Ltd. (IL) 2010-09-08 EP disclosed
EP-2226341-A2 Drying substances, preparation and use thereof Oridion Medical 1987 Ltd. (IL) 2010-09-08 EP disclosed
CN-101822950-A Drying substances, preparation and use thereof ORIDION MEDICAL 1987 LTD 2010-09-08 CN disclosed
CN-101822948-A Drying substances, preparation and use thereof ORIDION MEDICAL 1987 LTD 2010-09-08 CN disclosed
US-7604746-B2 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2009-10-20 US disclosed
EP-1747059-A1 PERVAPORATION COMPOSITE MEMBRANES McMaster University (CA) 2007-01-31 EP disclosed
US-20060000778-A1 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2006-01-05 US disclosed
WO-2005102503-A1 PERVAPORATION COMPOSITE MEMBRANES MCMASTER UNIVERSITY (CA) 2005-11-03 WO disclosed