Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SELL | P14151 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 2/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | HAAO | P46952 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985345 | 0.85 | GRM1 (0.42) | ACE2FABP3FABP4GRM1CYP1A2 | |
| SCHEMBL27821540 | 0.85 | GRM1 (0.45) | ACE2FABP3FABP4GRM1CYP1A2 | |
| SCHEMBL5611626 | 0.85 | ACE2 (0.47) | ACE2FABP3FABP4GRM1CYP1A2 | |
| SCHEMBL2943909 | 0.84 | ACE2 (0.50) | ACE2FABP3FABP4GRM1CYP1A2 | |
| SCHEMBL28753748 | 0.83 | GRM1 (0.47) | ACE2FABP3FABP4GRM1CYP1A2 | |
| SCHEMBL28068614 | 0.83 | GRM1 (0.44) | ACE2FABP3FABP4GRM1CYP1A2 | |
| SCHEMBL8879487 | 0.82 | ACE2 (0.49) | ACE2FABP3FABP4GRM1CYP1A2 | |
| SCHEMBL28134184 | 0.82 | GRM1 (0.41) | ACE2FABP3FABP4GRM1CYP1A2 | |
| SCHEMBL27749720 | 0.81 | TYR (0.42) | ACE2FABP3FABP4GRM1ALDH1A1 | |
| SCHEMBL27749718 | 0.81 | TYR (0.42) | ACE2FABP3FABP4GRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458883-A | Chlorine resistant polyethylene compounds and articles made therefrom | 弗纳技术股份有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-103002735-A | Modulators of 5-ht receptors and methods of use thereof | ABBVI CO | 2013-03-27 | — | — | CN | claimed |
| CN-1440385-A | Pyrrole derivatives for the treatment of AIDS | HOFFMANN LA ROCHE (CH) | 2003-09-03 | — | — | CN | claimed |
| CN-107793399-A | CDK4/6 inhibitor and its preparation method and application | 上海翰森生物医药科技有限公司 | 2018-03-13 | — | — | CN | disclosed |
| CN-104955824-B | It is used as the aminopyrimidine compounds of the inhibitor of the EGFR mutant containing T790M | 豪夫迈·罗氏有限公司 | 2017-09-22 | — | — | CN | disclosed |
| CN-106928219-A | Nitrogenous fused heterocyclic compound, preparation method, intermediate, composition and application | 上海医药集团股份有限公司 | 2017-07-07 | — | — | CN | disclosed |
| CN-106715574-A | Salts of etheramines and polymeric acids | 巴斯夫欧洲公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-106467517-A | The Abemaciclib derivant that deuterium is modified | 正大天晴药业集团股份有限公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-106458883-A | Chlorine resistant polyethylene compounds and articles made therefrom | 弗纳技术股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106188038-A | One class has the compound of kinase inhibiting activity, preparation method and purposes | 中国科学院上海药物研究所 | 2016-12-07 | — | — | CN | disclosed |
| CN-106083823-A | One class has the compound of kinase inhibiting activity, preparation method and purposes | 中国科学院上海药物研究所 | 2016-11-09 | — | — | CN | disclosed |
| CN-105732615-A | CDK kinase inhibitor | 山东轩竹医药科技有限公司 | 2016-07-06 | — | — | CN | disclosed |
| CN-105294655-A | CDK small-molecule inhibitor compounds and application therefore | GUANGDONG HEC PHARMACEUTICAL | 2016-02-03 | — | — | CN | disclosed |
| CN-103002735-B | Modulators of 5-ht receptors and methods of use thereof | ABBVI CO | 2015-05-20 | — | — | CN | disclosed |
| CN-103002735-A | Modulators of 5-ht receptors and methods of use thereof | ABBVI CO | 2013-03-27 | — | — | CN | disclosed |
| CN-1414951-A | Drug discharge pump inhibitor | FUNDAMENTAL THERAPEUTICAL INC (US) | 2003-04-30 | — | — | CN | disclosed |