Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 20/20 | 0.54 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.46 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15587364 | 1.00 | MAP4K4 (0.54) | MAP4K4MINK1TNIK | |
| Methyl Alcohol SCHEMBL18129025 | 0.94 | MAP4K4 (0.50) | MAP4K4 | |
| SCHEMBL25372089 | 0.83 | MAP4K4 (0.53) | MAP4K4MINK1TNIK | |
| SCHEMBL29439674 | 0.81 | MAP4K4 (0.38) | MAP4K4 | |
| SCHEMBL22715495 | 0.81 | MAP4K4 (0.38) | MAP4K4 | |
| SCHEMBL1724431 | 0.79 | EGFR (0.45) | MAP4K4 | |
| SCHEMBL1034679 | 0.76 | EGFR (0.43) | MAP4K4 | |
| SCHEMBL22715380 | 0.76 | EGFR (0.43) | MAP4K4 | |
| SCHEMBL23000191 | 0.76 | EGFR (0.43) | MAP4K4 | |
| SCHEMBL29439719 | 0.76 | EGFR (0.43) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119546602-A | Pyrrolidone derivatives as inhibitors of nfkb-induced kinase | 詹森药业有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-118908957-A | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-11-08 | — | — | CN | disclosed |
| WO-2024186839-A1 | BICYCLIC ARYL SULFONAMIDES, SULFONES, AND SULFONATE ESTERS AS ANTI-PARASITIC AGENTS | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2024-09-12 | — | — | WO | disclosed |
| CN-114222737-B | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-117500803-A | Amino-substituted heterocycles for the treatment of cancers with EGFR mutations | 纽威伦特公司 | 2024-02-02 | — | — | CN | disclosed |
| EP-3976597-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | Janssen Pharmaceutica NV (BE) | 2022-04-06 | — | — | EP | disclosed |