Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 9/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22715172 | 1.00 | ADORA1 (0.46) | ADORA1DHFRMAP4K4 | |
| SCHEMBL22715891 | 0.83 | DHFR (0.37) | ADORA1DHFRMAP4K4 | |
| SCHEMBL29439645 | 0.83 | DHFR (0.37) | ADORA1DHFRMAP4K4 | |
| SCHEMBL22715935 | 0.83 | DHFR (0.37) | ADORA1DHFRMAP4K4 | |
| SCHEMBL22716441 | 0.82 | DHFR (0.35) | DHFR | |
| SCHEMBL29439842 | 0.82 | DHFR (0.35) | DHFR | |
| SCHEMBL29439784 | 0.77 | ADORA1 (0.41) | ADORA1DHFRMAP4K4 | |
| SCHEMBL22715191 | 0.77 | ADORA1 (0.41) | ADORA1DHFRMAP4K4 | |
| SCHEMBL29439675 | 0.76 | DHFR (0.53) | DHFRMAP4K4 | |
| SCHEMBL3922711 | 0.76 | DHFR (0.53) | DHFRMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118908957-A | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-114222737-B | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-07-26 | — | — | CN | disclosed |
| EP-3976597-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | Janssen Pharmaceutica NV (BE) | 2022-04-06 | — | — | EP | disclosed |