Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28909799 | 1.00 | POLB (0.41) | POLBCHRM1DRD2CHRM4HTR7 | |
| SCHEMBL28534883 | 0.87 | POLB (0.48) | POLBCHRM1HSP90AA1HSD17B3AR | |
| SCHEMBL28528387 | 0.84 | POLB (0.57) | POLBDRD2CHRM4HTR7ALDH1A1 | |
| SCHEMBL29439763 | 0.84 | POLB (0.57) | POLBDRD2CHRM4HTR7ALDH1A1 | |
| SCHEMBL19899024 | 0.78 | NOTUM (0.39) | CHRM1DRD2HTR7HTR2CHTR2B | |
| SCHEMBL28540577 | 0.76 | POLB (0.46) | POLBDRD2CHRM4HTR7DRD1 | |
| SCHEMBL13881541 | 0.75 | HRH1 (0.41) | HTR7HSP90AA1PPIAARCNR1 | |
| SCHEMBL11490469 | 0.75 | POLB (0.50) | POLBDRD2CHRM4HTR7SLC6A2 | |
| SCHEMBL28526989 | 0.75 | POLB (0.45) | POLBDRD2HTR7PPIAHTR2B | |
| SCHEMBL8605029 | 0.74 | ACHE (0.51) | POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112441920-B | Method for copper photocatalytic synthesis of 9-acetoxyl-9, 10-dihydrophenanthrene compound | 浙江工业大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-112441921-B | Method for synthesizing 9-acetoxyl-9, 10-dihydrophenanthrene compound by virtue of iridium photocatalysis | 浙江工业大学 | 2022-03-18 | — | — | CN | disclosed |