Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGAV | P06756 | 2/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.40 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.40 |
| ▸ | UGCG | Q16739 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952766 | 1.00 | GPR139 (0.44) | GPR139PDE2AITGB3ITGAVITGB5 | |
| SCHEMBL28709108 | 1.00 | GPR139 (0.44) | GPR139PDE2AITGB3ITGAVITGB5 | |
| SCHEMBL21272729 | 0.89 | GPR139 (0.45) | GPR139PDE2AITGB3ITGAVITGB5 | |
| SCHEMBL21272728 | 0.89 | GPR139 (0.45) | GPR139PDE2AITGB3ITGAVITGB5 | |
| SCHEMBL29589674 | 0.89 | GPR139 (0.45) | GPR139PDE2AITGB3ITGAVITGB5 | |
| SCHEMBL21272605 | 0.89 | PDE2A (0.48) | GPR139PDE2AITGB3ITGAVITGB5 | |
| SCHEMBL21272603 | 0.89 | PDE2A (0.48) | GPR139PDE2AITGB3ITGAVITGB5 | |
| SCHEMBL21272738 | 0.87 | GPR139 (0.44) | GPR139PDE2AITGB3ITGAVITGB5 | |
| SCHEMBL22953247 | 0.87 | GPR139 (0.44) | GPR139PDE2AITGB3ITGAVITGB5 | |
| SCHEMBL21272741 | 0.87 | GPR139 (0.44) | GPR139PDE2AITGB3ITGAVITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206830-B | Alcohol derivatives as Kv7 potassium channel openers | H.隆德贝克有限公司 | 2024-07-30 | — | — | CN | disclosed |
| EP-4007634-A1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | H. Lundbeck A/S (DK) | 2022-06-08 | — | — | EP | disclosed |
| CN-114206830-A | Alcohol derivatives as Kv7 potassium channel openers | H.隆德贝克有限公司 | 2022-03-18 | — | — | CN | disclosed |