Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL885924 | 1.00 | MET (0.76) | METINSR | |
| SCHEMBL885923 | 1.00 | MET (0.76) | METINSR | |
| SCHEMBL2944076 | 1.00 | MET (0.76) | METINSR | |
| SCHEMBL885937 | 0.91 | MET (0.78) | METINSR | |
| SCHEMBL885936 | 0.91 | MET (0.78) | METINSR | |
| SCHEMBL885568 | 0.89 | MET (0.74) | METINSR | |
| SCHEMBL886250 | 0.89 | MET (0.74) | METINSR | |
| SCHEMBL885567 | 0.89 | MET (0.74) | METINSR | |
| SCHEMBL886140 | 0.86 | MET (1.00) | METINSR | |
| SCHEMBL2060693 | 0.86 | MET (0.78) | METINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222647-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | Cephalon, Inc. (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2008051547-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2008-05-02 | — | — | WO | disclosed |