Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | HTR2A | P28223 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | HTR1D | P28221 | 1/20 | 0.61 |
| ▸ | HTR1B | P28222 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | CTSK | P43235 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 3/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734204 | 1.00 | SLC6A4 (0.61) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL1518985 | 0.98 | SLC6A4 (0.59) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL1518996 | 0.98 | SLC6A4 (0.59) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL1518971 | 0.98 | SLC6A4 (0.59) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL1293186 | 0.98 | SLC6A4 (0.59) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL29391207 | 0.98 | SLC6A4 (0.59) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL28649099 | 0.98 | SLC6A4 (0.59) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL1518978 | 0.98 | SLC6A4 (0.59) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL1519001 | 0.98 | SLC6A4 (0.59) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL31366243 | 0.95 | SLC6A4 (0.63) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195695-B | Preparation method of 3- (4-hydroxybutyl) -1H-indole compound | 上海应用技术大学 | 2023-02-10 | — | — | CN | claimed |
| CN-114195695-A | Preparation method of 3- (4-hydroxybutyl) -1H-indole compound | 上海应用技术大学 | 2022-03-18 | — | — | CN | claimed |
| CN-114195695-B | Preparation method of 3- (4-hydroxybutyl) -1H-indole compound | 上海应用技术大学 | 2023-02-10 | — | — | CN | disclosed |
| CN-114195695-B | Preparation method of 3- (4-hydroxybutyl) -1H-indole compound | 上海应用技术大学 | 2023-02-10 | — | — | CN | disclosed |
| CN-114195695-B | Preparation method of 3- (4-hydroxybutyl) -1H-indole compound | 上海应用技术大学 | 2023-02-10 | — | — | CN | disclosed |
| CN-114195695-A | Preparation method of 3- (4-hydroxybutyl) -1H-indole compound | 上海应用技术大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-114195695-A | Preparation method of 3- (4-hydroxybutyl) -1H-indole compound | 上海应用技术大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-114195695-A | Preparation method of 3- (4-hydroxybutyl) -1H-indole compound | 上海应用技术大学 | 2022-03-18 | — | — | CN | disclosed |