Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | HTR2A | P28223 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | HTR1D | P28221 | 1/20 | 0.61 |
| ▸ | HTR1B | P28222 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | CTSK | P43235 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 3/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29441817 | 1.00 | SLC6A4 (0.61) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL1518985 | 0.98 | SLC6A4 (0.59) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL1518996 | 0.98 | SLC6A4 (0.59) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL1518971 | 0.98 | SLC6A4 (0.59) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL1293186 | 0.98 | SLC6A4 (0.59) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL29391207 | 0.98 | SLC6A4 (0.59) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL28649099 | 0.98 | SLC6A4 (0.59) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL1518978 | 0.98 | SLC6A4 (0.59) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL1519001 | 0.98 | SLC6A4 (0.59) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 | |
| SCHEMBL31366243 | 0.95 | SLC6A4 (0.63) | SLC6A4CYP3A4HTR2ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195695-B | Preparation method of 3- (4-hydroxybutyl) -1H-indole compound | 上海应用技术大学 | 2023-02-10 | — | — | CN | claimed |
| CN-114195695-A | Preparation method of 3- (4-hydroxybutyl) -1H-indole compound | 上海应用技术大学 | 2022-03-18 | — | — | CN | claimed |
| CN-114195695-B | Preparation method of 3- (4-hydroxybutyl) -1H-indole compound | 上海应用技术大学 | 2023-02-10 | — | — | CN | disclosed |
| CN-114195695-B | Preparation method of 3- (4-hydroxybutyl) -1H-indole compound | 上海应用技术大学 | 2023-02-10 | — | — | CN | disclosed |
| CN-114195695-B | Preparation method of 3- (4-hydroxybutyl) -1H-indole compound | 上海应用技术大学 | 2023-02-10 | — | — | CN | disclosed |
| CN-114195695-A | Preparation method of 3- (4-hydroxybutyl) -1H-indole compound | 上海应用技术大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-114195695-A | Preparation method of 3- (4-hydroxybutyl) -1H-indole compound | 上海应用技术大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-114195695-A | Preparation method of 3- (4-hydroxybutyl) -1H-indole compound | 上海应用技术大学 | 2022-03-18 | — | — | CN | disclosed |
| EP-3027607-B1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2020-08-26 | — | — | EP | disclosed |
| US-10316025-B2 | Substituted piperazine compounds and methods of use and use thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-06-11 | — | — | US | disclosed |
| CN-108456198-A | The preparation method of vilazodone or its hydrochloride | 江苏豪森药业集团有限公司 | 2018-08-28 | — | — | CN | disclosed |
| US-5807871-A | PSYCHOLOGICAL DISORDERS, ALZHEIMER OR PARKINSON DISEASE | H. LUNDBECK A/S (DK) | 1998-09-15 | — | — | US | disclosed |
| EP-0593511-B1 | PIPERIDINE DERIVATES HAVING ANXIOLYTIC EFFECT | LUNDBECK & CO AS H (DK) | 1998-09-02 | — | — | EP | disclosed |
| EP-0859004-A1 | Piperidine derivatives having anxiolytic effect | H. LUNDBECK A/S (DK) | 1998-08-19 | — | — | EP | disclosed |
| EP-0853085-A1 | Piperidine derivatives having anxiolytic effect | H. LUNDBECK A/S (DK) | 1998-07-15 | — | — | EP | disclosed |
| US-5665725-A | Piperidine derivatives having anxiolytic effect | Lundbeck, H. (DK) | 1997-09-09 | — | — | US | disclosed |
| EP-0593511-A1 | PIPERIDINE DERIVATES HAVING ANXIOLYTIC EFFECT | H. LUNDBECK A/S (DK) | 1994-04-27 | — | — | EP | disclosed |
| WO-1992022554-A1 | PIPERIDINE DERIVATES HAVING ANXIOLYTIC EFFECT | H. LUNDBECK A/S (DK) | 1992-12-23 | — | — | WO | disclosed |
| EP-0518805-A1 | Piperidine derivatives | H. LUNDBECK A/S (DK) | 1992-12-16 | — | — | EP | disclosed |
| EP-0007399-B1 | INDOLYLALKYL AMINES, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND PROCESS FOR THEIR MANUFACTURE | MERCK PATENT GmbH (DE) | 1982-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10316025-B2 | Substituted piperazine compounds and methods of use and use thereof | HTR5A, HTR2C, TPH1 | SLC6A4 14/4885CYP3A4 378/4885HTR2A 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.