Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.78 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26345520 | 1.00 | TLR8 (0.78) | TLR8HRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL20434306 | 0.88 | TLR8 (1.00) | TLR8MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2849398 | 0.86 | TLR8 (0.90) | TLR8MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL5791298 | 0.85 | TLR8 (0.88) | TLR8MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL8585646 | 0.84 | TLR8 (0.81) | TLR8MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL17985629 | 0.83 | TLR8 (0.69) | TLR8HRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL5792943 | 0.81 | TLR8 (0.66) | TLR8HRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL28265778 | 0.81 | CYP2D6 (0.68) | TLR8HRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL28043727 | 0.80 | HRH4 (0.56) | TLR8HRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL6128303 | 0.79 | TLR8 (0.69) | TLR8HRH3MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022046999-A1 | MODULATORS OF MYB-MEDIATED TRANSCRIPTION AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-03-03 | — | — | WO | disclosed |