Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20434306 | 0.89 | TLR8 (1.00) | TLR8MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2849398 | 0.88 | TLR8 (0.90) | TLR8MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL5791298 | 0.86 | TLR8 (0.88) | TLR8MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL6128303 | 0.85 | TLR8 (0.69) | TLR8MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL29442374 | 0.84 | TLR8 (0.78) | TLR8MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL26345520 | 0.84 | TLR8 (0.78) | TLR8MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL8597545 | 0.80 | CYP2D6 (0.70) | TLR8KMT2ACYP2D6HRH4GAA | |
| SCHEMBL16608745 | 0.79 | DNM2 (0.61) | TLR8MEN1KMT2ACYP1A2GAA | |
| SCHEMBL17985629 | 0.78 | TLR8 (0.69) | TLR8MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL13097151 | 0.78 | GAA (0.65) | TLR8MEN1KMT2ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998020878-A1 | 5-[φ-(SUBSTITUTED ARYL)ALKENYLENE AND ALKYNYLENE]-2,4-DIAMINOPYRIMIDINES AS PESTICIDES | FMC CORPORATION (US) | 1998-05-22 | — | — | WO | disclosed |
| US-5696259-A | 2,4-diamino-5-iodopyrimidines useful as pesticide intermediates | FMC CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| US-5622954-A | INSECTICIDE | FMC CORPORATION (US) | 1997-04-22 | — | — | US | disclosed |