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Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL2944296

C[C@@H]1C(=O)N(c2ccc(SC(F)(F)F)cc2)C(=O)N1Cc1ccncc1O.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.43

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Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ IGF1R P08069 16/20 0.43
▸ SMO Q99835 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL3727239 1.00 IGF1R (0.43) IGF1RSMO
SCHEMBL2934289 0.95 IGF1R (0.46) IGF1RSMO
SCHEMBL2934291 0.95 IGF1R (0.46) IGF1RSMO
Trifluoroacetic Acid SCHEMBL3741568 0.91 IGF1R (0.43) IGF1RSMO
Trifluoroacetic Acid SCHEMBL3727713 0.91 IGF1R (0.43) IGF1RSMO
SCHEMBL2934794 0.87 IGF1R (0.44) IGF1RSMO
Trifluoroacetic Acid SCHEMBL3726606 0.86 IGF1R (0.54) IGF1RSMO
Trifluoroacetic Acid SCHEMBL3734827 0.86 IGF1R (0.54) IGF1RSMO
SCHEMBL2940606 0.85 IGF1R (0.47) IGF1RSMO
SCHEMBL2939871 0.85 IGF1R (0.46) IGF1RSMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1599464-B1 NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS AVENTIS PHARMA SA (FR) 2010-09-22 — — EP claimed