Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | PDE4A | P27815 | 1/20 | 0.70 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.70 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MAOB | P27338 | 2/20 | 0.66 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.64 |
| ▸ | XDH | P47989 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30138922 | 0.90 | ABCG2 (0.82) | ABCG2MAPTPDE4APDE4BPDE4C | |
| SCHEMBL29443580 | 0.88 | MAPT (0.82) | ABCG2MAPTPDE4APDE4BPDE4C | |
| SCHEMBL30138726 | 0.86 | ABCG2 (0.75) | ABCG2MAPTPDE4APDE4BPDE4C | |
| SCHEMBL30138963 | 0.86 | ABCG2 (0.75) | ABCG2MAPTPDE4APDE4BPDE4C | |
| SCHEMBL19423222 | 0.85 | ABCG2 (0.74) | ABCG2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL18742755 | 0.85 | ABCG2 (0.73) | ABCG2MAPTPDE4APDE4BPDE4C | |
| SCHEMBL19182863 | 0.84 | ABCG2 (0.86) | ABCG2MAPTNPC1RAB9AKMT2A | |
| SCHEMBL19182862 | 0.84 | ABCG2 (0.86) | ABCG2MAPTNPC1RAB9AKMT2A | |
| SCHEMBL2462049 | 0.84 | MAPT (1.00) | ABCG2MAPTPDE4APDE4BPDE4C | |
| SCHEMBL2462050 | 0.84 | MAPT (1.00) | ABCG2MAPTPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433073-B | Preparation method and application of kava piperine B analogue | 兰州大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-115433073-A | Preparation method and application of kava piperine B analogue | 兰州大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-114426470-A | Application of human PCID2 protein in preparation or screening of antitumor drugs and compound with antitumor activity | 兰州大学第一医院 | 2022-05-03 | — | — | CN | disclosed |
| CN-112870363-B | Application of human PCID2 protein in preparation or screening of antitumor drugs and compound with antitumor activity | 兰州大学第一医院 | 2022-02-18 | — | — | CN | disclosed |