Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.82 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | PDE4A | P27815 | 1/20 | 0.67 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.67 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | XDH | P47989 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29443544 | 0.90 | ABCG2 (1.00) | ABCG2MAPTPDE4APDE4BPDE4C | |
| SCHEMBL30138963 | 0.86 | ABCG2 (0.75) | ABCG2MAPTPDE4APDE4BPDE4C | |
| SCHEMBL29443580 | 0.83 | MAPT (0.82) | ABCG2MAPTPDE4APDE4BPDE4C | |
| SCHEMBL2462049 | 0.82 | MAPT (1.00) | ABCG2MAPTPDE4APDE4BPDE4C | |
| SCHEMBL2462050 | 0.82 | MAPT (1.00) | ABCG2MAPTPDE4APDE4BPDE4C | |
| SCHEMBL30138726 | 0.81 | ABCG2 (0.75) | ABCG2MAPTPDE4APDE4BPDE4C | |
| SCHEMBL30138731 | 0.81 | ABCG2 (0.83) | ABCG2MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL18742755 | 0.80 | ABCG2 (0.73) | ABCG2MAPTPDE4APDE4BPDE4C | |
| SCHEMBL4609586 | 0.79 | MAPT (0.84) | ABCG2MAPTPDE4APDE4BPDE4C | |
| SCHEMBL16616651 | 0.79 | ABCG2 (0.72) | ABCG2MAPTPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433073-B | Preparation method and application of kava piperine B analogue | 兰州大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-115433073-A | Preparation method and application of kava piperine B analogue | 兰州大学 | 2022-12-06 | — | — | CN | disclosed |