Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.75 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.65 |
| ▸ | XDH | P47989 | 1/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18742697 | 1.00 | ABCG2 (0.75) | ABCG2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL29733424 | 0.90 | ABCG2 (0.61) | ABCG2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL28350603 | 0.90 | ABCG2 (0.61) | ABCG2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL29443563 | 0.90 | MAPT (0.82) | ABCG2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL25280331 | 0.87 | MAPT (0.78) | ABCG2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL25198778 | 0.87 | MAPT (0.78) | ABCG2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL30138915 | 0.86 | MAPT (0.76) | ABCG2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL29443572 | 0.86 | ABCG2 (1.00) | ABCG2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL4030789 | 0.85 | MAPT (1.00) | ABCG2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL4030793 | 0.85 | MAPT (1.00) | ABCG2MAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433073-B | Preparation method and application of kava piperine B analogue | 兰州大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-115433073-A | Preparation method and application of kava piperine B analogue | 兰州大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-114426470-A | Application of human PCID2 protein in preparation or screening of antitumor drugs and compound with antitumor activity | 兰州大学第一医院 | 2022-05-03 | — | — | CN | disclosed |
| CN-112870363-B | Application of human PCID2 protein in preparation or screening of antitumor drugs and compound with antitumor activity | 兰州大学第一医院 | 2022-02-18 | — | — | CN | disclosed |