Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18179634 | 0.76 | KDM4E (0.33) | ALDH1A1KDM4ERAPGEF4POLBMAPT | |
| SCHEMBL29151039 | 0.76 | ALDH1A1 (0.33) | ALDH1A1KDM4ERAPGEF4POLBMAPT | |
| SCHEMBL30472444 | 0.76 | ALDH1A1 (0.33) | ALDH1A1KDM4ERAPGEF4POLBMAPT | |
| SCHEMBL28476099 | 0.76 | ALDH1A1 (0.33) | ALDH1A1KDM4ERAPGEF4POLBMAPT | |
| SCHEMBL318571 | 0.76 | ALDH1A1 (0.33) | ALDH1A1KDM4ERAPGEF4POLBMAPT | |
| SCHEMBL30860724 | 0.76 | ALDH1A1 (0.33) | ALDH1A1KDM4ERAPGEF4POLBMAPT | |
| SCHEMBL14024390 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KDM4ERAPGEF4POLBMAPT | |
| Hydrochloric Acid SCHEMBL2800815 | 0.74 | ALDH1A1 (0.32) | ALDH1A1KDM4ERAPGEF4POLBMAPT | |
| Hydrochloric Acid SCHEMBL13721744 | 0.74 | ALDH1A1 (0.32) | ALDH1A1KDM4ERAPGEF4POLBMAPT | |
| Hydrochloric Acid SCHEMBL2800812 | 0.74 | ALDH1A1 (0.32) | ALDH1A1KDM4ERAPGEF4POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279696-B2 | Processes for the preparation of 7-{4-[4-(1-benzothiophen-4-yl) piperazin-1-yl]butoxy}quinolin-2(1H)-one | MSN LABORATORIES PRIVATE LIMITED (IN) | 2022-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11279696-B2 | Processes for the preparation of 7-{4-[4-(1-benzothiophen-4-yl) piperazin-1-yl]butoxy}quinolin-2(1H)-one | CYP1B1, CYP4B1, CYP1A1 | ALDH1A1 244/4885KDM4E 2318/4885RAPGEF4 1878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.