Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 18/20 | 0.77 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.60 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.60 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | JAK1 | P23458 | 1/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
| ▸ | JAK3 | P52333 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946927 | 1.00 | TTK (0.77) | TTKPIK3CBMAPK8PTK2ADORA3 | |
| SCHEMBL3706140 | 0.94 | TTK (0.69) | TTKPIK3CBMAPK8PTK2ADORA3 | |
| SCHEMBL3697853 | 0.93 | TTK (0.66) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL3702624 | 0.92 | TTK (0.66) | TTKPIK3CBMAPK8PTK2ADORA3 | |
| SCHEMBL2956334 | 0.92 | TTK (0.77) | TTKPIK3CBMAPK8PTK2ADORA3 | |
| SCHEMBL4766744 | 0.91 | TTK (0.65) | TTKPIK3CBMAPK8PTK2ADORA3 | |
| SCHEMBL4764715 | 0.91 | TTK (0.78) | TTKPIK3CBMAPK8PTK2ADORA3 | |
| SCHEMBL3709751 | 0.90 | TTK (0.63) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL4764673 | 0.90 | TTK (0.63) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL4764770 | 0.90 | TTK (0.63) | TTKPIK3CBMAPK8PTK2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |
| CN-114592061-A | Prognostic biomarkers for TTK inhibitor chemotherapy | 荷兰转化研究中心有限责任公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-107567503-B | Prognostic biomarkers for TTK inhibitor chemotherapy | 荷兰转化研究中心有限责任公司 | 2022-03-22 | — | — | CN | disclosed |