Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 20/20 | 0.63 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3697853 | 0.94 | TTK (0.66) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL3709751 | 0.91 | TTK (0.63) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL29446172 | 0.90 | TTK (0.77) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL2946927 | 0.90 | TTK (0.77) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL3714100 | 0.89 | TTK (0.60) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL3708904 | 0.89 | TTK (0.60) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL4766744 | 0.89 | TTK (0.65) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL3711952 | 0.87 | TTK (0.60) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL3706140 | 0.87 | TTK (0.69) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL21601586 | 0.85 | ADORA3 (0.60) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122840-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYREXIS, INC. (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120122840-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYREXIS, INC. (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122840-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | VHL, TP53, ASAH2 | TTK 4589/4885PIK3CB 2268/4885MAPK8 4343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.