Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.42 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 3/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.41 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.38 |
| ▸ | WNT1 | P04628 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13097046 | 0.81 | LRRK2 (0.44) | CLK2LRRK2AURKAAURKBINCENP | |
| SCHEMBL30274556 | 0.81 | LRRK2 (0.44) | CLK2LRRK2AURKAAURKBINCENP | |
| SCHEMBL23753887 | 0.80 | MTOR (0.43) | CLK2LRRK2AURKAAURKBINCENP | |
| SCHEMBL30274584 | 0.80 | CLK2 (0.43) | CLK2LRRK2AURKAAURKBINCENP | |
| SCHEMBL24007658 | 0.80 | CLK2 (0.43) | CLK2LRRK2AURKAAURKBINCENP | |
| SCHEMBL29961620 | 0.78 | CLK2 (0.56) | CLK2LRRK2CHEK1MKNK1MKNK2 | |
| SCHEMBL29961343 | 0.78 | CLK2 (0.56) | CLK2LRRK2AURKBCHEK1MKNK1 | |
| SCHEMBL24920777 | 0.78 | ACVR2A (0.46) | CLK2LRRK2AURKAAURKBINCENP | |
| SCHEMBL13086431 | 0.78 | IRAK1 (0.41) | CLK2LRRK2AURKAAURKBINCENP | |
| SCHEMBL24008090 | 0.76 | CLK2 (0.43) | CLK2LRRK2AURKAAURKBINCENP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114126613-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2022-03-01 | — | — | CN | disclosed |