SCHEMBL29447969

SCHEMBL29447969

c1ccc(CCN2C[C@H](OCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2COCc2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 3/20 0.55
SSTR5 P35346 3/20 0.55
BCHE P06276 3/20 0.49
ACHE P22303 3/20 0.49
GAA P10253 2/20 0.45
GBA1 P04062 3/20 0.38
UGCG Q16739 2/20 0.38
GBA2 Q9HCG7 2/20 0.38
CTSL P07711 1/20 0.37
CTSB P07858 1/20 0.37
CTSK P43235 1/20 0.37
HRH3 Q9Y5N1 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15721072 1.00 SSTR4 (0.55) SSTR4SSTR5BCHEACHEGAA
SCHEMBL30186530 0.94 SSTR4 (0.51) SSTR4SSTR5BCHEACHEGAA
SCHEMBL30186602 0.93 SSTR4 (0.50) SSTR4SSTR5BCHEACHEGAA
SCHEMBL15721065 0.93 SSTR4 (0.53) SSTR4SSTR5BCHEACHEGAA
SCHEMBL30186516 0.90 SSTR4 (0.48) SSTR4SSTR5BCHEACHEGAA
SCHEMBL30186614 0.89 SSTR4 (0.49) SSTR4SSTR5BCHEACHEGAA
SCHEMBL30186525 0.89 SSTR4 (0.49) SSTR4SSTR5BCHEACHEGAA
SCHEMBL21135110 0.89 SSTR4 (0.49) SSTR4SSTR5BCHEACHEGAA
SCHEMBL15721150 0.89 SSTR4 (0.49) SSTR4SSTR5BCHEACHEGBA1
SCHEMBL22657445 0.88 GAA (0.56) SSTR4SSTR5BCHEACHEGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114174263-B Non-lysosomal glucosylceramidase inhibitors and uses thereof 阿勒克图治疗公司 2025-01-10 CN disclosed
EP-3966199-A1 NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF Alectos Therapeutics Inc. (CA) 2022-03-16 EP disclosed
CN-114174263-A Non-lysosomal glucosylceramidase inhibitors and uses thereof 阿勒克图治疗公司 2022-03-11 CN disclosed