SCHEMBL21135110

SCHEMBL21135110

OCCN1C[C@@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1COCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 3/20 0.49
SSTR5 P35346 3/20 0.49
BCHE P06276 3/20 0.48
ACHE P22303 3/20 0.48
UGCG Q16739 7/20 0.42
GBA2 Q9HCG7 7/20 0.42
GBA1 P04062 6/20 0.42
PDE4D Q08499 1/20 0.40
GAA P10253 2/20 0.39
LCT P09848 4/20 0.37
SI P14410 3/20 0.37
MGAM O43451 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7036444 0.97 BCHE (0.48) SSTR4SSTR5BCHEACHEUGCG
SCHEMBL29447969 0.89 SSTR4 (0.55) SSTR4SSTR5BCHEACHEUGCG
SCHEMBL15721072 0.89 SSTR4 (0.55) SSTR4SSTR5BCHEACHEUGCG
SCHEMBL15721150 0.88 SSTR4 (0.49) SSTR4SSTR5BCHEACHEUGCG
SCHEMBL15721124 0.86 BCHE (0.50) SSTR4SSTR5BCHEACHEUGCG
SCHEMBL15721065 0.86 SSTR4 (0.53) SSTR4SSTR5BCHEACHEUGCG
SCHEMBL15095203 0.86 BCHE (0.51) SSTR4SSTR5BCHEACHEPDE4D
SCHEMBL17243613 0.85 SSTR4 (0.50) SSTR4SSTR5BCHEACHEUGCG
SCHEMBL19575247 0.85 SSTR4 (0.50) SSTR4SSTR5BCHEACHEUGCG
SCHEMBL20577640 0.85 SSTR4 (0.50) SSTR4SSTR5BCHEACHEUGCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10774043-B2 Glycolactam compounds, process for preparation and uses thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2020-09-15 US disclosed
US-20190194133-A1 GLYCOLACTAM COMPOUNDS, PROCESS FOR PREPARATION AND USES THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2019-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10774043-B2 Glycolactam compounds, process for preparation and uses thereof GMNN, C9, OGFR SSTR4 233/4885SSTR5 276/4885BCHE 52/4885
US-20190194133-A1 GLYCOLACTAM COMPOUNDS, PROCESS FOR PREPARATION AND USES THEREOF GALNT14, GALNT10, GALNT3 SSTR4 115/4885SSTR5 139/4885BCHE 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.