Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.46 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22777818 | 1.00 | GAA (0.59) | GAAL3MBTL1NR4A2PTPN1AAK1 | |
| SCHEMBL29448086 | 0.81 | HDAC6 (0.45) | GAAL3MBTL1NR4A2PTPN1HDAC6 | |
| SCHEMBL22777796 | 0.81 | HDAC6 (0.45) | GAAL3MBTL1NR4A2PTPN1HDAC6 | |
| SCHEMBL1590095 | 0.79 | FAAH (0.55) | GAANR4A2DAGLAKDM4ENPC1 | |
| SCHEMBL1675372 | 0.79 | HDAC6 (0.65) | GAAL3MBTL1HPSEHDAC6KDM4E | |
| SCHEMBL38651946 | 0.78 | ESR2 (0.53) | GAADAGLAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9757168 | 0.78 | ESR2 (0.53) | GAADAGLAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10730839 | 0.78 | KDM4E (0.56) | GAAL3MBTL1HPSEHDAC6AGPAT2 | |
| Hydrochloric Acid SCHEMBL23320558 | 0.78 | FAAH (0.54) | GAANR4A2DAGLAKDM4ENPC1 | |
| SCHEMBL3612583 | 0.78 | FAAH (0.54) | GAANR4A2DAGLAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114222729-A | Amino acid transport inhibitors and uses thereof | 范德比尔特大学 | 2022-03-22 | — | — | CN | claimed |
| US-20220304984-A1 | AMINO ACID TRANSPORT INHIBITORS AND THE USES THEREOF | VANDERBILT UNIVERSITY | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220304984-A1 | AMINO ACID TRANSPORT INHIBITORS AND THE USES THEREOF | SLC1A5, SLC7A11, SLC3A2 | GAA 1294/4885L3MBTL1 1013/4885NR4A2 3574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.