Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22777810 | 1.00 | HDAC1 (0.49) | HDAC1LDHAMAOBDHODHNPC1 | |
| SCHEMBL29448076 | 0.84 | HDAC1 (0.58) | HDAC1MAOBDHODHNPC1NFKB1 | |
| SCHEMBL22777816 | 0.84 | HDAC1 (0.58) | HDAC1MAOBDHODHNPC1NFKB1 | |
| SCHEMBL22777732 | 0.76 | BCL2L1 (0.51) | LDHADHODHRAB9AIDO1TDO2 | |
| SCHEMBL29448037 | 0.76 | BCL2L1 (0.51) | LDHADHODHRAB9AIDO1TDO2 | |
| SCHEMBL31167745 | 0.75 | PIK3CA (0.55) | NPC1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL22777775 | 0.74 | MAP4K4 (0.43) | HDAC1MAOBDHODHNFKB1NFKB2 | |
| SCHEMBL28727291 | 0.73 | SMN1; SMN2 (0.65) | HDAC1MAOBNPC1NFKB1NFKB2 | |
| SCHEMBL836745 | 0.73 | SMN1; SMN2 (0.65) | HDAC1MAOBNPC1NFKB1NFKB2 | |
| SCHEMBL22777740 | 0.73 | MEN1 (0.45) | HDAC1MAOBNPC1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114222729-A | Amino acid transport inhibitors and uses thereof | 范德比尔特大学 | 2022-03-22 | — | — | CN | claimed |
| US-20220304984-A1 | AMINO ACID TRANSPORT INHIBITORS AND THE USES THEREOF | VANDERBILT UNIVERSITY | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220304984-A1 | AMINO ACID TRANSPORT INHIBITORS AND THE USES THEREOF | SLC1A5, SLC7A11, SLC3A2 | HDAC1 4385/4885LDHA 1310/4885MAOB 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.