Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.65 |
| ▸ | RELA | Q04206 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28727291 | 1.00 | SMN1; SMN2 (0.65) | SMN1; SMN2RAB9AHPGDNPC1PKM | |
| SCHEMBL27714204 | 0.98 | SMN1; SMN2 (0.63) | SMN1; SMN2RAB9AHPGDNPC1PKM | |
| Hydrochloric Acid SCHEMBL3610419 | 0.98 | SMN1; SMN2 (0.63) | SMN1; SMN2RAB9AHPGDNPC1PKM | |
| Benzo[D]Thiazole SCHEMBL28216365 | 0.87 | ALDH1A1 (0.58) | SMN1; SMN2RAB9AHPGDNPC1PKM | |
| SCHEMBL6319718 | 0.86 | ALDH1A1 (0.66) | SMN1; SMN2RAB9AHPGDNPC1PKM | |
| SCHEMBL2732845 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9AHPGDNPC1PKM | |
| SCHEMBL2170056 | 0.84 | ALDH1A1 (0.64) | SMN1; SMN2RAB9AHPGDNPC1PKM | |
| SCHEMBL24751 | 0.83 | HSD17B1 (0.62) | SMN1; SMN2RAB9AHPGDNPC1PKM | |
| SCHEMBL14020195 | 0.83 | NPC1 (0.55) | SMN1; SMN2RAB9AHPGDNPC1PKM | |
| SCHEMBL369480 | 0.82 | ALDH1A1 (0.62) | SMN1; SMN2RAB9AHPGDNPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119977957-A | Small-molecule proteasome agonist and preparation method and application thereof | 杭州市第一人民医院(西湖大学附属杭州市第一人民医院) | 2025-05-13 | — | — | CN | claimed |
| CN-108350034-B | Antimicrobial polymyxin derived compounds | 莫纳什大学 | 2022-03-11 | — | — | CN | claimed |
| US-20170341956-A1 | SYSTEM FOR DYNAMIC FLUIDIZED LOADING OF A LIGAND UPON CARBON MEDIA AND METHODS ASSOCIATED THEREWITH | Tusaar Corp. | 2017-11-30 | — | — | US | claimed |
| CN-105198835-B | The synthesis technique of the formic acid of benzothiazole 2 | 上海泰坦科技股份有限公司 | 2017-09-29 | — | — | CN | claimed |
| CN-104860901-B | Preparation method of benzothiazole-2-carboxylic acid | 北京工业大学 | 2017-04-19 | — | — | CN | claimed |
| CN-105198835-A | Synthesizing process of benzothiazole-2-formic acid | SHANGHAI TITAN TECHNOLOGY CO LTD | 2015-12-30 | — | — | CN | claimed |
| CN-104860901-A | Preparation method of benzothiazole-2-carboxylic acid | UNIV BEIJING TECHNOLOGY | 2015-08-26 | — | — | CN | claimed |
| EP-2794490-A1 | SYSTEM FOR DYNAMIC FLUIDIZED LOADING OF A LIGAND UPON CARBON MEDIA AND METHODS ASSOCIATED THEREWITH | Tusaar Inc (US) | 2014-10-29 | — | — | EP | claimed |
| CN-103923765-A | Detergent Composition For Process Of Manufacturing Semiconductors And Displays | COWON INNOTECH INC | 2014-07-16 | — | — | CN | claimed |
| US-8598175-B2 | Heteroarylamide pyrimidone derivatives | SANOFI (FR) | 2013-12-03 | — | — | US | claimed |
| EP-2162443-A2 | HETEROARYLAMIDE-SUBSTITUTED PYRIMIDONE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | Sanofi-Aventis (FR) | 2010-03-17 | — | — | EP | claimed |
| US-20100022546-A1 | ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2010-01-28 | — | — | US | claimed |
| US-20090023741-A1 | ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AG (DE) | 2009-01-22 | — | — | US | claimed |
| WO-2008155666-A2 | HETEROARYLAMIDE-SUBSTITUTED PYRIMIDONE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SANOFI-AVENTIS (FR) | 2008-12-24 | — | — | WO | claimed |
| WO-2008152099-A2 | ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | claimed |
| EP-1992621-A1 | Heteroarylamide-substituted pyrimidone derivatives for the treatment of neurodegenerative diseases | Sanofi-Aventis (FR) | 2008-11-19 | — | — | EP | claimed |
| WO-2007138112-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |
| CN-1248968-A | Heteroaryl-hexanoic acid amide derivatives, their preparation and their use as selective inhibitors of MIP-1-alpha binding to its CCRI receptor | PFIZER (US) | 2000-03-29 | — | — | CN | claimed |
| EP-0966443-A1 | HETEROARYL-HEXANOIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS SELECTIVE INHIBITORS OF MIP-1-ALPHA BINDING TO ITS CCR1 RECEPTOR | PFIZER INC. (US) | 1999-12-29 | — | — | EP | claimed |
| WO-1998038167-A1 | HETEROARYL-HEXANOIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS SELECTIVE INHIBITORS OF MIP-1-ALPHA BINDING TO ITS CCR1 RECEPTOR | PFIZER INC. (US) | 1998-09-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022546-A1 | ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME | QDPR, ADM2, PDE3B | SMN1; SMN2 2444/4885RAB9A 314/4885HPGD 591/4885 |
| US-20090023741-A1 | ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR | PTGER2, PTGER1, PTGDR2 | SMN1; SMN2 4144/4885RAB9A 3569/4885HPGD 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.