Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 1/20 | 0.53 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 3/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | WEE1 | P30291 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22634468 | 1.00 | ULK1 (0.53) | ULK1ULK2MAPK9MAPK10BRD4 | |
| SCHEMBL29449048 | 0.90 | ULK1 (0.52) | ULK1ULK2MAPK9MAPK10BRD4 | |
| SCHEMBL22634458 | 0.90 | ULK1 (0.52) | ULK1ULK2MAPK9MAPK10BRD4 | |
| SCHEMBL22652087 | 0.90 | ULK1 (0.65) | ULK1ULK2MAPK9MAPK10BRD4 | |
| SCHEMBL22634554 | 0.90 | ULK1 (0.53) | ULK1ULK2MAPK9MAPK10BRD4 | |
| SCHEMBL29448982 | 0.90 | ULK1 (0.53) | ULK1ULK2MAPK9MAPK10BRD4 | |
| SCHEMBL29449166 | 0.89 | ULK1 (0.49) | ULK1ULK2MAPK9MAPK10BRD4 | |
| SCHEMBL22634498 | 0.89 | ULK1 (0.49) | ULK1ULK2MAPK9MAPK10BRD4 | |
| SCHEMBL22634665 | 0.88 | ULK1 (0.42) | ULK1ULK2MAPK9MAPK10PTK2 | |
| SCHEMBL29449119 | 0.88 | ULK1 (0.42) | ULK1ULK2MAPK9MAPK10PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966207-A1 | PHENYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF | Deciphera Pharmaceuticals, LLC (US) | 2022-03-16 | — | — | EP | claimed |
| EP-3966207-A1 | PHENYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF | Deciphera Pharmaceuticals, LLC (US) | 2022-03-16 | — | — | EP | disclosed |