Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 10/20 | 0.55 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.55 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.54 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28127 | 1.00 | PDE7A (0.55) | PDE7APDE7BGSTP1GSTM2KMT2A | |
| SCHEMBL8668348 | 0.88 | PDE7A (0.62) | PDE7APDE7BGSTP1GSTM2KMT2A | |
| SCHEMBL11429284 | 0.83 | TDP1 (0.52) | PDE7APDE7BGSTP1GSTM2KMT2A | |
| SCHEMBL16225668 | 0.82 | GSTP1 (0.54) | PDE7APDE7BGSTP1GSTM2KMT2A | |
| SCHEMBL11409450 | 0.82 | GSTP1 (0.54) | PDE7AGSTP1GSTM2KMT2AMEN1 | |
| SCHEMBL27225074 | 0.82 | GSTP1 (0.54) | GSTP1GSTM2KMT2AMEN1CYP1A2 | |
| SCHEMBL17784719 | 0.81 | GSTP1 (0.53) | GSTP1GSTM2KMT2AMEN1CYP1A2 | |
| SCHEMBL5376331 | 0.81 | MEN1 (0.65) | PDE7AGSTP1GSTM2KMT2AMEN1 | |
| SCHEMBL2777612 | 0.80 | PDE7A (0.55) | PDE7APDE7BKMT2AMAPK1TSHR | |
| SCHEMBL11415231 | 0.79 | PDE7A (0.52) | PDE7APDE7BGSTP1GSTM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111961005-B | Phenyl uracil compound and application thereof | 南北兄弟药业投资有限公司 | 2022-04-12 | — | — | CN | disclosed |