SCHEMBL29449409

SCHEMBL29449409

O=C(CBr)c1cccc(Br)n1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
GRM5 P41594 1/20 0.45
PTPN1 P18031 6/20 0.43
GSK3B P49841 7/20 0.42
KDM4E B2RXH2 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
ACMSD Q8TDX5 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CTSA P10619 1/20 0.40
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP1A2 P05177 1/20 0.36
HTR7 P34969 1/20 0.35
MAPK10 P53779 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3508261 1.00 ALDH1A1 (0.50) ALDH1A1HPGDGRM5PTPN1GSK3B
Pyridine SCHEMBL8706849 0.90 ALDH1A1 (0.47) ALDH1A1HPGDGRM5PTPN1GSK3B
SCHEMBL28712036 0.87 KDM4E (0.52) PTPN1GSK3BKDM4EALOX15TSHR
SCHEMBL15988712 0.86 ALDH1A1 (0.51) ALDH1A1HPGDGRM5KDM4EALOX15
SCHEMBL31096237 0.84 ALDH1A1 (0.50) ALDH1A1HPGDGRM5KDM4EALOX15
SCHEMBL3508834 0.84 ALDH1A1 (0.50) ALDH1A1HPGDGRM5KDM4EALOX15
SCHEMBL13135972 0.82 ALDH1A1 (0.49) ALDH1A1HPGDGRM5KDM4EALOX15
SCHEMBL6564811 0.82 ALDH1A1 (0.49) ALDH1A1HPGDGRM5KDM4EALOX15
SCHEMBL3511203 0.82 ALDH1A1 (0.49) ALDH1A1HPGDGRM5KDM4EALOX15
Hydrochloric Acid SCHEMBL2865450 0.81 ALDH1A1 (0.47) ALDH1A1HPGDGRM5KDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114181230-B Liquid-liquid extracting agent for separating sulfate ions and preparation method thereof 山西大学 2023-03-10 CN claimed
CN-114181230-A Liquid-liquid extracting agent for separating sulfate ions and preparation method thereof 山西大学 2022-03-15 CN claimed
CN-113166177-B Boron-containing PDE4 inhibitors 辉瑞公司 2024-09-03 CN disclosed
CN-114181230-B Liquid-liquid extracting agent for separating sulfate ions and preparation method thereof 山西大学 2023-03-10 CN disclosed
CN-114181230-A Liquid-liquid extracting agent for separating sulfate ions and preparation method thereof 山西大学 2022-03-15 CN disclosed