Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001749 | 0.87 | CCR3 (0.51) | CCR3CCR5ABL1RIN1USP30 | |
| SCHEMBL3840449 | 0.87 | CCR3 (0.51) | CCR3CCR5ABL1RIN1USP30 | |
| SCHEMBL17103472 | 0.86 | CCR3 (0.47) | CCR3CCR5ABL1RIN1USP30 | |
| SCHEMBL17103469 | 0.86 | CCR3 (0.47) | CCR3CCR5ABL1RIN1USP30 | |
| SCHEMBL1635974 | 0.85 | CCR3 (0.46) | CCR3CCR5ABL1RIN1USP30 | |
| SCHEMBL17103610 | 0.81 | CCR3 (0.44) | CCR3CCR5ABL1RIN1USP30 | |
| SCHEMBL17103611 | 0.81 | CCR3 (0.44) | CCR3CCR5ABL1RIN1USP30 | |
| SCHEMBL7403462 | 0.81 | CCR3 (0.47) | CCR3CCR5ABL1RIN1USP30 | |
| SCHEMBL13744920 | 0.81 | ACHE (0.51) | CCR3CCR5ABL1RIN1USP30 | |
| SCHEMBL14506645 | 0.81 | ACHE (0.51) | CCR3CCR5ABL1RIN1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279854-B | Preparation method of 7H-pyrrolo [2,3-d ] pyrimidine compound | 常州齐晖药业有限公司 | 2022-04-05 | — | — | CN | disclosed |