SCHEMBL2945

SCHEMBL2945

O=[C]Oc1cccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 4/20 0.46
PGR P06401 1/20 0.46
GAA P10253 1/20 0.46
PTGS1 P23219 1/20 0.46
MAPK1 P28482 1/20 0.46
HTR1B P28222 5/20 0.46
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TSHR P16473 2/20 0.44
KCNA3 P22001 1/20 0.43
OGG1 O15527 1/20 0.42
HTR1D P28221 1/20 0.42
SLC6A4 P31645 1/20 0.41
HRH1 P35367 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL778458 0.88 HPRT1 (0.52) ALDH1A1KDM4ETDP1HPGDHSD17B10
SCHEMBL21832135 0.88 HPRT1 (0.52) ALDH1A1KDM4ETDP1HPGDHSD17B10
SCHEMBL301216 0.82 ALDH1A1 (0.42) ALDH1A1KDM4ETDP1HPGDHSD17B10
SCHEMBL21832129 0.80 ALDH1A1 (0.41) ALDH1A1KDM4ETDP1HPGDHSD17B10
SCHEMBL21832126 0.80 ALDH1A1 (0.41) ALDH1A1KDM4ETDP1HPGDHSD17B10
SCHEMBL21832127 0.80 ALDH1A1 (0.41) ALDH1A1KDM4ETDP1HPGDHSD17B10
SCHEMBL21832148 0.80 ALDH1A1 (0.48) ALDH1A1KDM4ETDP1HPGDHSD17B10
SCHEMBL8061684 0.80 KMT2A (0.57) ALDH1A1KDM4ETDP1HPGDHSD17B10
SCHEMBL10870661 0.79 HTR1B (0.47) ALDH1A1KDM4ETDP1HPGDHSD17B10
SCHEMBL1127922 0.78 HTR1B (0.46) ALDH1A1KDM4ETDP1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12881 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024062998-A1 POLYMER, RESIST COMPOSITION CONTAINING SAID POLYMER, METHOD FOR MANUFACTURING MEMBER USING SAME, AND PATTERN FORMATION METHOD 東洋合成工業株式会社 2024-03-28 WO claimed
CN-107976867-B Photosensitive composition and method for forming cured film 东京应化工业株式会社 2024-03-01 CN claimed
CN-117466813-A Meta-aminobenzoic acid bisamide compound and intermediate thereof 湖南化工研究院有限公司 2024-01-30 CN claimed
EP-3816153-B1 HETEROCYCLIC COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICALS CO (JP) 2023-10-18 EP claimed
CN-109749066-B Liquid crystal polyester, liquid crystal polyester composition and product prepared from liquid crystal polyester composition 金发科技股份有限公司 2022-01-11 CN claimed
CN-106483764-B Photosensitive composition, pattern forming method, cured product, and display device 东京应化工业株式会社 2021-03-30 CN claimed
US-10781276-B2 Polymer, resist composition containing polymer, and method for manufacturing device using same TOYO GOSEI CO., LTD. (JP) 2020-09-22 US claimed
US-20180273664-A1 POLYMER, RESIST COMPOSITION CONTAINING POLYMER, AND METHOD FOR MANUFACTURING DEVICE USING SAME TOYO GOSEI CO., LTD. (JP) 2018-09-27 US claimed
US-9935269-B2 Electroluminescence element Konica Minolta, Inc. (JP) 2018-04-03 US claimed
US-9730940-B2 Purine inhibitors of human phosphatidylinositol 3-kinase delta MERCK SHARP & DOHME (US) 2017-08-15 US claimed
US-4180571-A Arylmalonamido-1-oxadethiacephalosporins SHIONOGI & CO., LTD. (JP) 1979-12-25 US claimed
EP-0002826-A1 Novel phosphoramidothioate derivatives, pesticidal compositions containing them, processes for preparing the novel derivatives and the use of the novel derivatives for combating pests ROHM AND HAAS COMPANY (US) 1979-07-11 EP claimed
US-4138570-A METHINE DYE BAYER AKTIENGESELLSCHAFT (DE) 1979-02-06 US claimed
US-4092474-A Cephalosporins having a metaloxy group in 3-substituent SHIONOGI & CO., LTD. (JA) 1978-05-30 US claimed
US-4091210-A Preparation of 3-alkyl-3-cephem-4-carboxylic acid compounds from dithio isopropenyl azetidine carboxylic compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1978-05-23 US claimed
US-4017557-A WIRE JACKETING, HOSE, BELTS, SEALS, GASKETS, LOW PRESSURE TIRES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-12 US claimed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US claimed
US-3993646-A Process for the ring expansion of penicillins to cephalosporin compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-11-23 US claimed
US-3991042-A Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus BAYER AKTIENGESELLSCHAFT (DT) 1976-11-09 US claimed
US-3948877-A POLYACRYLONITRILE, ACID MODIFIED POLYESTERS OR POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-04-06 US claimed