Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.68 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.61 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.61 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | IKZF2 | Q9UKS7 | 10/20 | 0.53 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL25267613 | 1.00 | CRBN (0.68) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL25242337 | 0.96 | CRBN (0.72) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL29450148 | 0.96 | CRBN (0.72) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL30496980 | 0.91 | CRBN (0.66) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL25741105 | 0.89 | CRBN (0.61) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL25225380 | 0.87 | CRBN (0.63) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL25741860 | 0.86 | CRBN (0.58) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL31043517 | 0.85 | CRBN (0.62) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL23357926 | 0.85 | CRBN (0.62) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL29944315 | 0.85 | CRBN (0.62) | CRBNGSPT1DDB1IKZF3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457344-A | Low molecular weight protein degradation agent and application thereof | 凯普托尔治疗学股份有限公司 | 2023-07-18 | — | — | CN | disclosed |
| EP-4188373-A1 | LOW MOLECULAR WEIGHT PROTEIN DEGRADERS AND THEIR APPLICATIONS | Captor Therapeutics S.A. (PL) | 2023-06-07 | — | — | EP | disclosed |
| WO-2022029138-A1 | LOW MOLECULAR WEIGHT PROTEIN DEGRADERS AND THEIR APPLICATIONS | CAPTOR THERAPEUTICS S.A. (PL) | 2022-02-10 | — | — | WO | disclosed |