SCHEMBL30496980

SCHEMBL30496980

CCCNCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O

nearest known ligand 0.66

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 10/20 0.66
▸ GSPT1 P15170 2/20 0.62
▸ DDB1 Q16531 2/20 0.62
▸ IKZF3 Q9UKT9 1/20 0.62
▸ CYP2C19 P33261 1/20 0.58
▸ KCNH2 Q12809 1/20 0.58
▸ IKZF2 Q9UKS7 10/20 0.57
▸ CSNK1A1 P48729 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29450148 0.94 CRBN (0.72) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL25242337 0.94 CRBN (0.72) CRBNGSPT1DDB1IKZF3CYP2C19
Formic Acid SCHEMBL29450118 0.91 CRBN (0.68) CRBNGSPT1DDB1IKZF3CYP2C19
Formic Acid SCHEMBL25267613 0.91 CRBN (0.68) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL31043517 0.90 CRBN (0.62) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL25225380 0.90 CRBN (0.63) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL25740848 0.89 CRBN (0.67) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL15850466 0.88 CRBN (0.68) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL1413760 0.88 CRBN (0.68) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL25741105 0.88 CRBN (0.61) CRBNGSPT1DDB1IKZF3CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116457344-A Low molecular weight protein degradation agent and application thereof 凯普托尔治疗学股份有限公司 2023-07-18 — — CN disclosed
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