Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.37 |
| ▸ | PARP3 | Q9Y6F1 | 3/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 4/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450905 | 0.88 | LDHA (0.42) | FLT3GSK3BABCB1ABCG2LDHA | |
| SCHEMBL29450900 | 0.84 | ABCG2 (0.40) | FLT3GSK3BABCB1ABCG2LDHA | |
| SCHEMBL29450967 | 0.83 | BRD4 (0.43) | ABCB1ABCG2LDHAMIFMAPK14 | |
| SCHEMBL29451023 | 0.79 | MAPK14 (0.41) | FLT3GSK3BABCB1ABCG2LDHA | |
| SCHEMBL29450896 | 0.79 | MAPK14 (0.50) | FLT3GSK3BABCB1ABCG2LDHA | |
| SCHEMBL29450882 | 0.78 | MIF (0.45) | PARP1ABCB1ABCG2LDHAMIF | |
| SCHEMBL29450982 | 0.78 | LDHA (0.44) | ABCB1ABCG2LDHAMIFMAPK14 | |
| SCHEMBL29450908 | 0.78 | LDHA (0.41) | FLT3GSK3BABCB1ABCG2LDHA | |
| SCHEMBL29450866 | 0.78 | LDHA (0.43) | FLT3GSK3BABCB1ABCG2LDHA | |
| SCHEMBL21160009 | 0.76 | MAPT (0.47) | PARP1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144520-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2022-03-04 | — | — | CN | claimed |
| CN-114144520-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2022-03-04 | — | — | CN | disclosed |