Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29451792 | 0.86 | HSD17B10 (0.41) | SMN1; SMN2MAPK1ABCG2NR1H3ALDH1A1 | |
| SCHEMBL6209103 | 0.79 | GAA (0.46) | SMN1; SMN2MAPK1PLA2G1BATG4BPOLB | |
| SCHEMBL3885989 | 0.79 | NR1H3 (0.34) | SMN1; SMN2NR1H2NR1H3ALDH1A1KDM4E | |
| SCHEMBL3885986 | 0.79 | NR1H3 (0.34) | SMN1; SMN2NR1H2NR1H3ALDH1A1KDM4E | |
| SCHEMBL6209098 | 0.79 | GAA (0.46) | SMN1; SMN2MAPK1PLA2G1BATG4BPOLB | |
| SCHEMBL14967314 | 0.78 | HDAC1 (0.51) | CA12CA1CA2CA9CA14 | |
| SCHEMBL14967548 | 0.78 | HDAC1 (0.51) | CA12CA1CA2CA9CA14 | |
| SCHEMBL9805467 | 0.78 | HDAC1 (0.51) | CA12CA1CA2CA9CA14 | |
| SCHEMBL9339908 | 0.78 | CA1 (0.51) | CA12CA1CA2CA9CA14 | |
| SCHEMBL11858178 | 0.78 | CA1 (0.51) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022032144-A1 | SUBSTRATE ADAPTOR INHIBITORS OF PRMT5 AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2022-02-10 | — | — | WO | disclosed |