Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 7/20 | 0.94 |
| ▸ | CA1 | P00915 | 2/20 | 0.94 |
| ▸ | CA4 | P22748 | 2/20 | 0.94 |
| ▸ | CA6 | P23280 | 2/20 | 0.94 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.94 |
| ▸ | CA2 | P00918 | 1/20 | 0.94 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.94 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.94 |
| ▸ | ITGAL | P20701 | 1/20 | 0.94 |
| ▸ | ADK | P55263 | 1/20 | 0.94 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indole SCHEMBL30877947 | 1.00 | AHR (0.94) | AHRCA1CA4CA6TRPA1 | |
| Indole SCHEMBL6386255 | 0.97 | AHR (0.90) | AHRCA1CA4CA6TRPA1 | |
| Indole SCHEMBL28071644 | 0.97 | AHR (1.00) | AHRCA1CA4CA6TRPA1 | |
| Indole SCHEMBL29352896 | 0.97 | — | — | |
| Indole SCHEMBL698 | 0.97 | — | — | |
| Indole SCHEMBL30463845 | 0.97 | — | — | |
| Indole SCHEMBL1160186 | 0.97 | AHR (1.00) | AHRCA1CA4CA6TRPA1 | |
| Indole SCHEMBL30250492 | 0.97 | — | — | |
| Indole SCHEMBL25404194 | 0.94 | AHR (0.94) | AHRCA1CA4CA6TRPA1 | |
| Indole SCHEMBL3538342 | 0.94 | AHR (0.94) | AHRCA1CA4CA6TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200904-A | Indole compound and preparation method and application thereof | 广东工业大学 | 2021-08-03 | — | — | CN | claimed |
| CN-110467555-B | Axial chiral aryl indole compound and synthesis method thereof | 江苏师范大学 | 2020-11-24 | — | — | CN | claimed |
| CN-105218427-B | Two amidine analog derivatives containing double amidino groups indoles benzene and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2018-05-25 | — | — | CN | claimed |
| CN-105218427-A | Contain two amidine analog derivatives of two amidino groups indoles benzene and its preparation method and application | INST MED BIOTECHNOLOGY CAMS | 2016-01-06 | — | — | CN | claimed |
| US-7611546-B2 | Composition comprising at least one substituted acetylenic carbocyanin derivative, process for treating keratin fibres using it, and device therefor | L'OREAL S.A. (FR) | 2009-11-03 | — | — | US | claimed |
| EP-1997475-A2 | Composition comprising at least one substituted derivative of acetylenic carbocyanine, method of treating keratinous fibres implementing it and device | L'Oréal (FR) | 2008-12-03 | — | — | EP | claimed |
| CN-118344339-A | Small molecule compounds targeting BCL 9/beta-catenin interactions | 江苏明生聚太生物科技有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118324746-A | Small molecule compounds targeting BCL 9/beta-catenin interactions | 江苏明生聚太生物科技有限公司 | 2024-07-12 | — | — | CN | disclosed |
| WO-2024146643-A1 | COMPOUND CONTAINING 2-METHYL-2-(3-(PIPERIDIN-3-YL)PHENOXY)-2-METHYLPROPANAMIDE SKELETON | 江苏明生聚太生物科技有限公司 | 2024-07-11 | — | — | WO | disclosed |
| CN-118119623-A | Targeted protease degradation (TED) platform | 嘉兴优博生物技术有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-118047787-A | 2,1, 3-Benzothiadiazole and spiropyran conjugated fluorescent compound and application thereof in lipid drop imaging | 山东大学 | 2024-05-17 | — | — | CN | disclosed |
| CN-112574255-B | Organic arsine-based CDK inhibitor and preparation method and application thereof | 中国科学院上海有机化学研究所 | 2024-05-10 | — | — | CN | disclosed |
| CN-111471046-B | Carbazole indole quinone derivative and preparation method and application thereof | 中国科学院成都有机化学有限公司 | 2024-04-05 | — | — | CN | disclosed |
| EP-1283836-A2 | NEUROPROTECTIVE AND ANTI-PROLIFERATIVE COMPOUNDS | Aegera Therapeutics Inc. (CA) | 2003-02-19 | — | — | EP | disclosed |
| CN-1383452-A | Compsns. and methods for treating cells having double minute DNA | NEWBIOTICS INC (US) | 2002-12-04 | — | — | CN | disclosed |
| WO-2001087887-A2 | NEUROPROTECTIVE AND ANTI-PROLIFERATIVE COMPOUNDS | AEGERA THERAPEUTICS INC. (CA) | 2001-11-22 | — | — | WO | disclosed |
| CN-1301982-A | Silver halide photographic emulsion and photosensitive material using said emulsion | FUJI PHOTO FILM CO LTD (JP) | 2001-07-04 | — | — | CN | disclosed |
| CN-1267884-A | Optical information recording media and optical information recording method | TAIYO YUDEN KK (JP) | 2000-09-27 | — | — | CN | disclosed |
| US-4816586-A | Delta opioid receptor antagonists | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1989-03-28 | — | — | US | disclosed |
| WO-1989000995-A1 | DELTA OPIOID RECEPTOR ANTAGONISTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1989-02-09 | — | — | WO | disclosed |