Indole

Indole

SCHEMBL6386255

OO.c1ccc2[nH]ccc2c1

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 7/20 0.90
TRPA1 O75762 1/20 0.90
CA1 P00915 1/20 0.90
CA2 P00918 1/20 0.90
ITGB2 P05107 1/20 0.90
ICAM1 P05362 1/20 0.90
ITGAL P20701 1/20 0.90
CA4 P22748 1/20 0.90
CA6 P23280 1/20 0.90
ADK P55263 1/20 0.90
NPC1 O15118 2/20 0.54
TYR P14679 1/20 0.48
USP2 O75604 1/20 0.48
GAA P10253 1/20 0.48
ALOX15 P16050 1/20 0.48
RAD51 Q06609 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
ALDH1A1 P00352 2/20 0.47
ENPP2 Q13822 2/20 0.47
KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indole SCHEMBL2945202 0.97 AHR (0.94) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL30877947 0.97 AHR (0.94) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL28071644 0.95 AHR (1.00) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL29352896 0.95
Indole SCHEMBL698 0.95
Indole SCHEMBL30463845 0.95
Indole SCHEMBL1160186 0.95 AHR (1.00) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL30250492 0.95
Indole SCHEMBL6791278 0.92 AHR (0.85) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL15007820 0.92 AHR (0.85) AHRTRPA1CA1CA2ITGB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111662316-B Indole hydrogen peroxide fluorescent probe and preparation method thereof 南通大学 2022-04-12 CN claimed
CN-111662316-A Indole hydrogen peroxide fluorescent probe and preparation method thereof 南通大学 2020-09-15 CN claimed
US-20050118123-A1 Use of chemiluminescence in cosmetics & chromatography VAIDYA NITEEN A (US) 2005-06-02 US claimed
CN-117447704-A Hyperbranched polysiloxane bioactive material capable of visually removing active oxygen and preparation method thereof 西北工业大学 2024-01-26 CN disclosed
CN-111662316-B Indole hydrogen peroxide fluorescent probe and preparation method thereof 南通大学 2022-04-12 CN disclosed
CN-111662316-B Indole hydrogen peroxide fluorescent probe and preparation method thereof 南通大学 2022-04-12 CN disclosed
CN-111662316-B Indole hydrogen peroxide fluorescent probe and preparation method thereof 南通大学 2022-04-12 CN disclosed
CN-111662316-A Indole hydrogen peroxide fluorescent probe and preparation method thereof 南通大学 2020-09-15 CN disclosed
CN-111662316-A Indole hydrogen peroxide fluorescent probe and preparation method thereof 南通大学 2020-09-15 CN disclosed
CN-111662316-A Indole hydrogen peroxide fluorescent probe and preparation method thereof 南通大学 2020-09-15 CN disclosed