Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733083 | 1.00 | HPGD (0.77) | HPGDL3MBTL1LMNAHSD17B10HTT | |
| SCHEMBL1201521 | 1.00 | HPGD (0.77) | HPGDL3MBTL1LMNAHSD17B10HTT | |
| SCHEMBL29417938 | 1.00 | HPGD (0.77) | HPGDL3MBTL1LMNAHSD17B10HTT | |
| SCHEMBL1201517 | 1.00 | HPGD (0.77) | HPGDL3MBTL1LMNAHSD17B10HTT | |
| Water SCHEMBL5462177 | 0.98 | HPGD (0.74) | HPGDL3MBTL1LMNAHSD17B10HTT | |
| SCHEMBL27741637 | 0.98 | HPGD (0.74) | HPGDL3MBTL1LMNAHSD17B10HTT | |
| Hydrochloric Acid SCHEMBL18956239 | 0.98 | HPGD (0.74) | HPGDL3MBTL1LMNAHSD17B10HTT | |
| Hydrochloric Acid SCHEMBL30295054 | 0.98 | HPGD (0.74) | HPGDL3MBTL1LMNAHSD17B10HTT | |
| SCHEMBL1204352 | 0.87 | L3MBTL1 (0.92) | HPGDL3MBTL1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL2217559 | 0.87 | HPGD (1.00) | HPGDL3MBTL1LMNAHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204020-A1 | METHOD OF TREATING PSMA-EXPRESSING CANCERS | Advanced Accelerator Applications International S.A. (CH) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022043558-A1 | METHOD OF TREATING PSMA-EXPRESSING CANCERS | ADVANCED ACCELERATOR APPLICATIONS INTERNATIONAL SA (CH) | 2022-03-03 | — | — | WO | disclosed |