Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 15/20 | 0.75 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2944434 | 0.86 | MLYCD (0.69) | MLYCDNR1H2NR1H3 | |
| SCHEMBL6846355 | 0.84 | MLYCD (0.67) | MLYCDNR1H2NR1H3 | |
| SCHEMBL2942014 | 0.84 | MLYCD (0.70) | MLYCDNR1H2NR1H3 | |
| SCHEMBL4883103 | 0.84 | MLYCD (0.63) | MLYCDNR1H2NR1H3 | |
| SCHEMBL6844036 | 0.83 | MLYCD (0.87) | MLYCDNR1H2NR1H3 | |
| SCHEMBL6843869 | 0.83 | MLYCD (1.00) | MLYCD | |
| SCHEMBL2943141 | 0.82 | MLYCD (0.61) | MLYCDNR1H2NR1H3 | |
| SCHEMBL2941948 | 0.79 | MLYCD (0.57) | MLYCDNR1H2NR1H3 | |
| SCHEMBL2945331 | 0.79 | MLYCD (0.78) | MLYCDNR1H2NR1H3 | |
| SCHEMBL2938718 | 0.79 | MLYCD (0.81) | MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4503232-B2 | — | — | 2010-07-14 | — | — | JP | claimed |
| JP-2004521113-A | — | — | 2004-07-15 | — | — | JP | claimed |
| EP-1353662-A2 | METHODS FOR THE TREATMENT OF DISEASES USING MALONYL-COA DECARBOX YLASE INHIBITORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-10-22 | — | — | EP | claimed |
| WO-2002058690-A2 | METHODS FOR THE TREATMENT OF DISEASES USING MALONYL-COA DECARBOX YLASE INHIBITORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-08-01 | — | — | WO | claimed |