Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4359880 | 0.68 | MAPT (0.36) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| SCHEMBL2725134 | 0.62 | GRIN1 (0.35) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| SCHEMBL3570167 | 0.62 | IDH1 (0.38) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| Methane SCHEMBL3623097 | 0.61 | GRIN1 (0.34) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| SCHEMBL23595492 | 0.59 | GRIN1 (0.60) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| SCHEMBL23596039 | 0.59 | GRIN1 (0.60) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| SCHEMBL23595794 | 0.59 | GRIN1 (0.60) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| SCHEMBL23595889 | 0.59 | GRIN1 (0.60) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| SCHEMBL23595731 | 0.59 | GRIN1 (0.60) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| SCHEMBL23595506 | 0.59 | GRIN1 (0.60) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141161-A1 | 3-cyanopyrrolidinyl-phenyl-oxazolidinones as antibacterial agents | Ferrer Internacional, S.A. (ES) | 2010-01-06 | — | — | EP | disclosed |