Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3570167 | 0.79 | IDH1 (0.38) | IDH1HSD11B1GRIN1GRIN2AGRIN2B | |
| SCHEMBL2725134 | 0.76 | GRIN1 (0.35) | MAPTIDH1HSD11B1GRIN1GRIN2A | |
| Methane SCHEMBL3623097 | 0.75 | GRIN1 (0.34) | MAPTIDH1HSD11B1GRIN1GRIN2A | |
| SCHEMBL7812799 | 0.71 | ALDH1A1 (0.35) | IDH1HSD11B1ALDH1A1KMT2APOLB | |
| SCHEMBL3578040 | 0.70 | IDH1 (0.33) | MAPTIDH1GRIN1GRIN2AALDH1A1 | |
| Propene SCHEMBL3656717 | 0.70 | GRIN1 (0.33) | IDH1HSD11B1GRIN1GRIN2AGRIN2B | |
| SCHEMBL20340441 | 0.69 | IDH1 (0.46) | MAPTIDH1HSD11B1ALDH1A1GAA | |
| Acetamide SCHEMBL3579500 | 0.68 | ALDH1A1 (0.35) | MAPTIDH1GRIN1GRIN2AALDH1A1 | |
| SCHEMBL2945348 | 0.68 | GRIN1 (0.40) | HSD11B1GRIN1GRIN2AGRIN2BGRIN2D | |
| SCHEMBL5418053 | 0.67 | IDH1 (0.38) | IDH1ALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072513-A1 | A cyano piperidinyl-phenil-oxazolidinone and use thereof | Ferrer Internacional, S.A. (ES) | 2009-06-24 | — | — | EP | disclosed |