SCHEMBL29453602

SCHEMBL29453602

Cc1ccc(N)cc1[N+](=O)[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 1.00
ALDH1A1 P00352 7/20 1.00
CYP3A4 P08684 5/20 1.00
RECQL P46063 1/20 1.00
TDP1 Q9NUW8 4/20 0.64
ALOX15 P16050 2/20 0.64
HSD17B10 Q99714 2/20 0.60
MAPK1 P28482 2/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
CES2 O00748 1/20 0.49
CES1 P23141 1/20 0.49
CASP1 P29466 2/20 0.48
MEN1 O00255 1/20 0.45
NPC1 O15118 1/20 0.45
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45
RAB9A P51151 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CRHBP P24387 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL100616 1.00 TSHR (1.00) TSHRALDH1A1CYP3A4RECQLTDP1
SCHEMBL27801297 0.85 TSHR (0.73) TSHRALDH1A1CYP3A4RECQLTDP1
SCHEMBL2767398 0.83 ALDH1A1 (0.71) TSHRALDH1A1CYP3A4RECQLTDP1
SCHEMBL845718 0.83 ALDH1A1 (0.71) TSHRALDH1A1CYP3A4RECQLTDP1
SCHEMBL5685395 0.82 TSHR (0.68) TSHRALDH1A1CYP3A4RECQLTDP1
SCHEMBL8188539 0.82 ALDH1A1 (0.67) TSHRALDH1A1CYP3A4RECQLTDP1
Hydrochloric Acid SCHEMBL6573276 0.81 TSHR (0.66) TSHRALDH1A1CYP3A4RECQLTDP1
Hydrochloric Acid SCHEMBL5687862 0.81 TSHR (0.66) TSHRALDH1A1CYP3A4RECQLTDP1
SCHEMBL1254184 0.80 TDP1 (0.72) TSHRALDH1A1CYP3A4RECQLTDP1
SCHEMBL11592046 0.79 ALDH1A1 (0.65) TSHRALDH1A1CYP3A4RECQLTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022228846-A1 METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER BASF SE (DE) 2022-11-03 WO claimed
WO-2022228846-A1 METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER BASF SE (DE) 2022-11-03 WO disclosed
EP-3980126-A1 BENZO[H][1,6] NAPHTHYRIDIN-2(1H)-ONES AS BMX INHIBITORS, FOR USE AGAINST CANCER Instituto de Medicina Molecular João Lobo Antunes (PT) 2022-04-13 EP disclosed