SCHEMBL29454483

SCHEMBL29454483

N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CS)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ DPP3 Q9NY33 5/20 0.57
▸ NTSR2 O95665 1/20 0.54
▸ NTSR1 P30989 1/20 0.54
▸ SORT1 Q99523 1/20 0.54
▸ CAPN1 P07384 2/20 0.51
▸ CTSB P07858 2/20 0.51
▸ OPRM1 P35372 1/20 0.51
▸ ECE1 P42892 5/20 0.50
▸ DPP4 P27487 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454493 1.00 DPP3 (0.57) DPP3NTSR2NTSR1SORT1CAPN1
SCHEMBL31452913 0.91 DPP3 (0.61) DPP3OPRM1
SCHEMBL29963309 0.90 DPP3 (0.64) DPP3NTSR2NTSR1SORT1CAPN1
SCHEMBL30272514 0.89 DPP3 (0.57) DPP3NTSR2NTSR1SORT1CAPN1
SCHEMBL29498733 0.89 DPP3 (0.63) DPP3ECE1DPP4
SCHEMBL30310835 0.87 DPP3 (0.57) DPP3NTSR2NTSR1SORT1CAPN1
SCHEMBL31474499 0.87 DPP4 (0.61) DPP3NTSR2NTSR1SORT1OPRM1
SCHEMBL30610091 0.87 DPP3 (0.69) DPP3NTSR2NTSR1SORT1OPRM1
SCHEMBL29648960 0.87 DPP3 (0.69) DPP3NTSR2NTSR1SORT1OPRM1
SCHEMBL30827785 0.87 DPP3 (0.60) DPP3NTSR2NTSR1SORT1CAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024111590-A1 COMPOSITION CONTAINING RAS INHIBITOR PEPTIDE 一丸ファルコス株式会社 2024-05-30 — — WO claimed
US-20220227813-A1 Ras INHIBITORY PEPTIDE ICHIMARU PHARCOS CO., LTD. (JP) 2022-07-21 — — US claimed
EP-3970801-A1 RAS INHIBITORY PEPTIDE Ichimaru Pharcos Co., Ltd. (JP) 2022-03-23 — — EP claimed
WO-2024111590-A1 COMPOSITION CONTAINING RAS INHIBITOR PEPTIDE 一丸ファルコス株式会社 2024-05-30 — — WO disclosed
US-20220227813-A1 Ras INHIBITORY PEPTIDE ICHIMARU PHARCOS CO., LTD. (JP) 2022-07-21 — — US disclosed
EP-3970801-A1 RAS INHIBITORY PEPTIDE Ichimaru Pharcos Co., Ltd. (JP) 2022-03-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220227813-A1 Ras INHIBITORY PEPTIDE RSU1, RASGRP1, RASSF5 DPP3 2838/4885NTSR2 134/4885NTSR1 96/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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