Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118240 | 1.00 | NPSR1 (0.39) | NPSR1HPGDALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL22118241 | 1.00 | NPSR1 (0.39) | NPSR1HPGDALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL15868733 | 0.85 | CYP11B1 (0.47) | NPSR1HPGDALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL14698346 | 0.85 | CYP11B1 (0.47) | NPSR1HPGDALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL22118232 | 0.84 | FNTA (0.35) | NPSR1ALDH1A1CYP11B1CYP11B2MAPT | |
| SCHEMBL15863578 | 0.84 | NPSR1 (0.39) | NPSR1HPGDALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL15863579 | 0.84 | NPSR1 (0.39) | NPSR1HPGDALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL14263011 | 0.80 | MAPT (0.53) | NPSR1ALDH1A1CYP11B1CYP11B2MAPT | |
| SCHEMBL1300477 | 0.79 | L3MBTL1 (0.40) | NPSR1HPGDALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL1300478 | 0.79 | L3MBTL1 (0.40) | NPSR1HPGDALDH1A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980414-A1 | BICYCLIC DERIVATIVES FOR TREATING ENDOPARASITES | Elanco Tiergesundheit AG (CH) | 2022-04-13 | — | — | EP | disclosed |