Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | FGF1 | P05230 | 2/20 | 0.38 |
| ▸ | VEGFA | P15692 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30392003 | 1.00 | LMNA (0.44) | LMNASMN1; SMN2TGM2HTTL3MBTL1 | |
| SCHEMBL30891263 | 0.97 | HTT (0.43) | LMNASMN1; SMN2TGM2HTTL3MBTL1 | |
| SCHEMBL30391643 | 0.97 | HTT (0.43) | LMNASMN1; SMN2TGM2HTTL3MBTL1 | |
| SCHEMBL20510407 | 0.94 | HTT (0.42) | LMNASMN1; SMN2TGM2HTTL3MBTL1 | |
| SCHEMBL16621421 | 0.91 | EPHX2 (0.43) | HTTSIRT2FGF1VEGFA | |
| SCHEMBL30891477 | 0.91 | HTT (0.47) | LMNASMN1; SMN2TGM2HTTL3MBTL1 | |
| SCHEMBL30891352 | 0.91 | FOLH1 (0.42) | FOLH1SIRT2 | |
| SCHEMBL30891397 | 0.89 | SIRT2 (0.48) | FOLH1SIRT2 | |
| SCHEMBL23575125 | 0.89 | EPHX2 (0.41) | HTTFOLH1SIRT2FGF1VEGFA | |
| SCHEMBL23497304 | 0.89 | FOLH1 (0.42) | FOLH1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4436610-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A TETRA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | Merck Sharp & Dohme LLC (US) | 2024-10-02 | — | — | EP | disclosed |
| WO-2023091441-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A TETRA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | MERCK SHARP & DOHME LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| EP-3980052-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2022-04-13 | — | — | EP | disclosed |