Brodifacoum

Brodifacoum

SCHEMBL29455095

O=c1oc2ccccc2c(O)c1C1CC(c2ccc(-c3ccc(Br)cc3)cc2)Cc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VKORC1 Q9BQB6 2/20 1.00
THRB P10828 1/20 0.42
NQO1 P15559 3/20 0.41
TNKS O95271 1/20 0.38
LMNA P02545 2/20 0.38
HPGD P15428 1/20 0.38
TOP2A P11388 1/20 0.38
HTR2A P28223 2/20 0.37
HTR2C P28335 2/20 0.37
HTR2B P41595 2/20 0.37
HRH3 Q9Y5N1 2/20 0.37
PRNP P04156 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
TP53 P04637 2/20 0.36
CTSK P43235 1/20 0.36
KDM4E B2RXH2 2/20 0.36
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 1/20 0.35
ABCB11 O95342 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Brodifacoum SCHEMBL435133 1.00 VKORC1 (1.00) VKORC1THRBNQO1TNKSLMNA
SCHEMBL10688149 0.94 VKORC1 (0.89) VKORC1THRBNQO1TNKSLMNA
SCHEMBL24003588 0.93 VKORC1 (0.86) VKORC1NQO1LMNAHPGDPRNP
SCHEMBL29904783 0.93 VKORC1 (0.86) VKORC1NQO1LMNAHPGDPRNP
SCHEMBL122474 0.93 VKORC1 (0.86) VKORC1NQO1LMNAHPGDPRNP
SCHEMBL29455127 0.93 VKORC1 (0.86) VKORC1NQO1LMNAHPGDPRNP
SCHEMBL9642577 0.92 VKORC1 (0.85) VKORC1THRBNQO1TNKSLMNA
SCHEMBL9641963 0.92 VKORC1 (0.85) VKORC1THRBNQO1TNKSLMNA
SCHEMBL9642008 0.92 VKORC1 (0.85) VKORC1THRBNQO1TNKSLMNA
SCHEMBL9640911 0.92 VKORC1 (0.85) VKORC1THRBNQO1TNKSLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024039525-A9 METHOD AND APPARATUS FOR ACCELERATING A VEHICLE IN A GRAVITATIONAL FIELD NANIA CRISTINA (US) 2024-05-16 WO claimed
WO-2024039525-A2 METHOD AND APPARATUS FOR ACCELERATING A VEHICLE IN A GRAVITATIONAL FIELD NANIA CRISTINA (US) 2024-02-22 WO claimed
EP-4688144-A1 COMPOUNDS AS GLP-1R AGONISTS Terns Pharmaceuticals, Inc. (US) 2026-02-11 EP disclosed
US-12519853-B2 Computer system and management method for computer system HITACHI VANTARA, LTD. (JP) 2026-01-06 US disclosed
US-20250204535-A1 Rodenticide PelGen Limited (GB) 2025-06-26 US disclosed
US-20250175524-A1 COMPUTER SYSTEM AND MANAGEMENT METHOD FOR COMPUTER SYSTEM HITACHI, LTD. (JP) 2025-05-29 US disclosed
EP-4499665-A2 RODENTICIDE Pelgen Limited (GB) 2025-02-05 EP disclosed
CN-119173523-A Rodenticide 佩尔根有限公司 2024-12-20 CN disclosed
WO-2024206878-A1 COMPOUNDS AS GLP-1R AGONISTS TERNS PHARMACEUTICALS, INC. (US) 2024-10-03 WO disclosed
CN-114357546-B Multi-scale optimization design method for gradient random lattice/porous structure 武汉大学 2024-06-25 CN disclosed
CN-117873388-A Data writing method, device, computer equipment and storage medium 天津中科曙光存储科技有限公司 2024-04-12 CN disclosed
CN-112445540-B Program running method, system, terminal and storage medium 惠州市创荣发智能科技有限公司 2023-05-09 CN disclosed
CN-115645235-A Multi-scene-oriented intelligent shifting machine system 国家康复辅具研究中心 2023-01-31 CN disclosed
WO-2022214485-A1 USE OF ANTI-CLOTTING COMPOUNDS AS RODENTICIDES BIOROXX GMBH (DE) 2022-10-13 WO disclosed
EP-4070658-A1 USE OF ANTICOAGULANT ACTIVE COMPOUNDS AS RODENTICIDE BIORoxx GmbH (DE) 2022-10-12 EP disclosed
CN-108829959-B Service-driven-oriented distribution network thematic map automatic generation method 广东电网有限责任公司 2022-09-06 CN disclosed
CN-113066515-B Optical disc recording method, computing equipment and readable storage medium 统信软件技术有限公司 2022-04-29 CN disclosed
EP-3981442-A1 MOBILE DEVICE OPERABLE BY MEANS OF A TEMPERATURE DIFFERENCE FOR CLEANING AND DISINFECTING ROOM AIR Münch, Elke (DE) 2022-04-13 EP disclosed
EP-3978038-A1 MOBILE DEVICE OPERABLE BY MEANS OF A TEMPERATURE DIFFERENCE FOR CLEANING AND DISINFECTING ROOM AIR AND TEST DEVICE FOR SAME Münch, Elke (DE) 2022-04-06 EP disclosed
CN-113885809-B Data management system and method 云和恩墨(北京)信息技术有限公司 2022-03-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250204535-A1 Rodenticide VIP, TNNI3, ANPEP VKORC1 2949/4885THRB 1106/4885NQO1 4821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.