SCHEMBL2945516

SCHEMBL2945516

CCCCO[Si](OC(C)=O)(OC(C)=O)OC(C)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
ATM Q13315 1/20 0.39
TSHR P16473 5/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CES2 O00748 1/20 0.36
HPGD P15428 1/20 0.36
HCAR2 Q8TDS4 1/20 0.34
NAAA Q02083 1/20 0.33
DGKA P23743 1/20 0.33
CYP3A4 P08684 1/20 0.33
PTGS2 P35354 1/20 0.33
CES1 P23141 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
PDE4A P27815 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
HDAC10 Q969S8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7563296 0.96 ALDH1A1 (0.52) ALDH1A1ATMTSHRTDP1L3MBTL1
SCHEMBL204725 0.96 ALDH1A1 (0.52) ALDH1A1ATMTSHRTDP1L3MBTL1
SCHEMBL15661900 0.89 ALDH1A1 (0.45) ALDH1A1TSHRCES2HCAR2NAAA
SCHEMBL29249906 0.86 ALDH1A1 (0.39) ALDH1A1TSHRCES2HCAR2
SCHEMBL15662777 0.85 ALDH1A1 (0.42) ALDH1A1ATMTSHRTDP1L3MBTL1
SCHEMBL11335573 0.82 ALDH1A1 (0.39) ALDH1A1TSHRCES2HCAR2
SCHEMBL10940919 0.82 TSHR (0.52) ALDH1A1ATMTSHRTDP1L3MBTL1
SCHEMBL3740993 0.81 ALDH1A1 (0.50) ALDH1A1ATMTSHRTDP1L3MBTL1
SCHEMBL2351633 0.81 ALDH1A1 (0.50) ALDH1A1ATMTSHRTDP1L3MBTL1
SCHEMBL6116158 0.78 TSHR (0.52) ALDH1A1ATMTSHRTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661960-B1 COATING COMPOSITION AND LOW DIELECTRIC SILICEOUS MATERIAL PRODUCED BY USING SAME AZ ELECTRONIC MATERIALS USA (US) 2012-07-25 EP claimed
US-7754003-B2 Coating composition and low dielectric siliceous material produced by using same AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-07-13 US claimed
EP-1661960-B1 COATING COMPOSITION AND LOW DIELECTRIC SILICEOUS MATERIAL PRODUCED BY USING SAME AZ ELECTRONIC MATERIALS USA (US) 2012-07-25 EP disclosed
CN-1836017-B Coating composition and low dielectric siliceous material produced by using same AZ ELECTRONIC MATERIALS JAPAN 2011-11-02 CN disclosed
US-7754003-B2 Coating composition and low dielectric siliceous material produced by using same AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-07-13 US disclosed
US-20060246303-A1 Coating composition and low dielectric siliceous material produced by using same MERCK PATENT GMBH (DE) 2006-11-02 US disclosed
CN-1836017-A Coating composition and low dielectric siliceous material produced by using same AZ ELECTRONIC MATERIALS JAPAN (JP) 2006-09-20 CN disclosed
EP-1661960-A1 COATING COMPOSITION AND LOW DIELECTRIC SILICEOUS MATERIAL PRODUCED BY USING SAME AZ Electronic Materials USA Corp. (US) 2006-05-31 EP disclosed
US-5171787-A Blends; high strength, heat, cold and oil resistance JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-12-15 US disclosed
EP-0405461-A2 Silicone-based composite rubber composition and uses thereof JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-01-02 EP disclosed
EP-0240952-A2 A method for producing a flaky material SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed